Results 71 to 80 of about 35,025 (266)

A critical evaluation of the effect of population size and phenotypic measurement on QTL detection and localization using a large F2 murine mapping population

Genetics and Molecular Biology, 2006
Population size and phenotypic measurement are two key factors determining the detection power of quantitative trait loci (QTL) mapping. We evaluated how these two controllable factors quantitatively affect the detection of QTL and their localization ...
Xinmin Li, Richard J Quigg, Jian Zhou, Shizhong Xu, Godfred Masinde, Subburaman Mohan, David J. Baylink   +6 more
doaj   +1 more source

A spatiotemporal single‐cell atlas of porcine development reveals regulatory dynamics and cellular targets of domestication

iMeta, EarlyView.
This study presents a cross‐tissue, single‐cell/single‐nucleus transcriptomic atlas spanning from prenatal to postnatal developmental stages in pig, characterizing 83 distinct cell types from 252,033 cells. Through the construction of cross‐tissue transcriptional regulatory networks and pseudotime trajectories, we revealed that organogenesis is driven ...
Rong Zhou, Zishuai Wang, Chenghao Hu, Shuhan Deng, Changyun Cai, Yanfang Wang, Shang‐Tong Li, Lijing Bai, Kui Li   +8 more
wiley   +1 more source

Of buds and bits: a meta-QTL study identifies stable QTL for berry quality and yield traits in cranberry mapping populations (Vaccinium macrocarpon Ait.)

Frontiers in Plant Science
IntroductionFor nearly two centuries, cranberry (Vaccinium macrocarpon Ait.) breeders have improved fruit quality and yield by selecting traits on fruiting stems, termed “reproductive uprights.” Crop improvement is accelerating rapidly in contemporary ...
Andrew F. Maule, Andrew F. Maule, Jenyne Loarca, Jenyne Loarca, Luis Diaz-Garcia, Hector Lopez-Moreno, Hector Lopez-Moreno, Jennifer Johnson-Cicalese, Jennifer Johnson-Cicalese, Nicholi Vorsa, Nicholi Vorsa, Massimo Iorizzo, Massimo Iorizzo, Jeffrey L. Neyhart, Juan E. Zalapa   +14 more
doaj   +1 more source

A simulation study on the accuracy of position and effect estimates of linked QTL and their asymptotic standard deviations using multiple interval mapping in an F₂ scheme

Genetics Selection Evolution, 2004
Approaches like multiple interval mapping using a multiple-QTL model for simultaneously mapping QTL can aid the identification of multiple QTL, improve the precision of estimating QTL positions and effects, and are able to identify patterns and ...
Freyer Gertraude, Liu Yuefu, Mayer Manfred   +2 more
doaj   +1 more source

Enviromics crosstalk between internal and external plant environments for enhanced adaptation and de novo domestication

iMeta, EarlyView.
Climate change demands accelerated plant adaptation and de novo domestication. Yet current enviromics focuses disproportionately on external environments, neglecting internal dynamics—gene expression, metabolic flux, and signal transduction—within predictive envirotyping frameworks.
Lin‐An Zhang, Xuan Dong, Kai Liu, Nicolas Gonzalez, Jose Manuel Estevez, Wen‐Xue Li, Xing Wang Deng, Feng Yu, Yunbi Xu   +8 more
wiley   +1 more source

PEMETAAN QUANTITATIVE TRAIT LOCI UNTUK SIFAT BERSKALA KATEGORIK

Jurnal Ilmu Pertanian Indonesia, 2007
Genes or regions on chromosome underlying a quantitative trait are called quantitative trait loci (QTL). Characterizing genes controlling quantitative trait on their position in chromosome and their effect on trait is through a process called QTL mapping.
Farit Mochamad Afendi
doaj  

MVQTLCIM: composite interval mapping of multivariate traits in a hybrid F1 population of outbred species

BMC Bioinformatics, 2017
Background With the plummeting cost of the next-generation sequencing technologies, high-density genetic linkage maps could be constructed in a forest hybrid F1 population. However, based on such genetic maps, quantitative trait loci (QTL) mapping cannot
Fenxiang Liu, Chunfa Tong, Shentong Tao, Jiyan Wu, Yuhua Chen, Dan Yao, Huogen Li, Jisen Shi   +7 more
doaj   +1 more source

Beyond the Classics: The Synergy of AI and Genomics Reveals an Expanded Repertoire of Pigmentation Genes

Journal of Experimental Zoology Part B: Molecular and Developmental Evolution, EarlyView.
Classical approaches for coloration analysis are limited by human low‐resolution phenotyping and genetic analysis. Artificial intelligence allows us to find genes beyond the tip of the iceberg that explain color and pattern diversity in nature. ABSTRACT Pigmentation has long served as a powerful system for exploring gene–trait relationships, yet much ...
Ehsan Pashay Ahi, Nidal Karagic
wiley   +1 more source

Haplotypic QTL mapping in an outbred pedigree

Genetical Research, 2003
An offspring genome can be viewed as a mosaic of chromosomal segments or haplotypes contributed by multiple founders in any quantitative trait locus (QTL) detection study but tracing these is especially complex to achieve for outbred pedigrees. QTL haplotypes can be traced from offspring back to individual founders in outbred pedigrees by combining ...
David P, Gwaze, Yi, Zhou, M Humberto, Reyes-Valdés, Mohammad A, Al-Rababah, Claire G, Williams   +4 more
openaire   +2 more sources

Omics GWAS: A Multi‐Omics Integrative Analysis Platform for Genome‐Wide Association Studies

Med Research, EarlyView.
ABSTRACT With the rapid advancement of genome‐wide association studies (GWAS), downstream analyses of GWAS data have become essential for elucidating the genetic mechanisms that underlie complex diseases. However, current post‐GWAS analyses face numerous challenges, including heterogeneous data formats, challenges in multi‐omics integration, and ...
Xu Zhang, Kailai Li, Yasi Zhang, Cenwen Liu, Shunyi Huang, Yingzhao Jin, Yugeng Gao, Quan Cheng, Yunyun Mei   +8 more
wiley   +1 more source