Results 81 to 90 of about 1,229,479 (285)

An SNP-based second-generation genetic map of Daphnia magna and its application to QTL analysis of phenotypic traits [PDF]

, 2014
Background: Although Daphnia is increasingly recognized as a model for ecological genomics and biomedical research, there is, as of yet, no high-resolution genetic map for the genus.
Ebert, Dieter, Dieter Ebert, Colbourne, John, Colbourne, J., De Meester, Luc, Anurag Chaturvedi, Beisel, Christian, Luc De Meester, Thomas, W. K., Hall, Matthew D., Stephens, Melissa T, De Meester, L., Thomas, W Kelley, Albere, B., Matthew D Hall, W Thomas, Thomas, W. Kelley, Eleanne Solorzano, Jeong-Hyeon Choi, Melissa T Stephens, Bergeron, R. Daniel, Routtu, J., Solorzano, E., Pfrender, Michael E., Brian Albere, Albere, Brian, Claus-Peter Stelzer, John Colbourne, Choi, Jeong-Hyeon, Stephens, M. T., Bergeron, R Daniel, Bergeron, R. D., Stelzer, Claus-Peter, Stelzer, C. P., Solorzano, Eleanne, Jarkko Routtu, Stephens, Melissa T., Choi, J. H., Beisel, C., Colbourne, John; id_orcid, Chaturvedi, A., R Bergeron, Chaturvedi, Anurag, Christian Beisel, Routtu, Jarkko, Pfrender, Michael E, Pfrender, M. E., Michael E Pfrender, Hall, M. D., Bergeron RD, De Meester L, Stephens MT, Colbourne J, Routtu J, Thomas WK, Ebert D, Chaturvedi A, Albere B, Beisel C, Stelzer CP, Hall MD, Choi JH, Solorzano E, Pfrender ME   +63 more
core   +1 more source

Developing a strain‐dependent susceptibility to hepatocellular carcinoma in a murine model based on histopathological evidence and genetic context

Animal Models and Experimental Medicine, EarlyView.
Using F1 (C57BL/6J/Smad4+/− X CC) mice, we found that partial loss of Smad4 promotes liver carcinogenesis in a strain‐dependent manner, highlighting the importance of genetic modifiers in tumor susceptibility. The use of Collaborative Cross mice provides a valuable platform for uncovering genotype‐specific cancer susceptibilities in preclinical ...
Osayd Zohud, Aysar Nashef, Imad Abu‐Elnaaj, Fuad A. Iraqi   +3 more
wiley   +1 more source

The efficiency of designs for fine-mapping of quantitative trait loci using combined linkage disequilibrium and linkage

Genetics Selection Evolution, 2004
In a simulation study, different designs were compared for efficiency of fine-mapping of QTL. The variance component method for fine-mapping of QTL was used to estimate QTL position and variance components.
Werf Julius, Lee Sang
doaj   +1 more source

Insight into the genetic components of community genetics: QTL mapping of insect association in a fast-growing forest tree [PDF]

, 2013
Identifying genetic sequences underlying insect associations on forest trees will improve the understanding of community genetics on a broad scale. We tested for genomic regions associated with insects in hybrid poplar using quantitative trait loci (QTL)
Katalin Tuba (486875), Katalin Tuba, Viger, Maud, Ferenc Lakatos (486874), Tuba, K., Gail Taylor, Smulders, M.J.M., Maud Viger (486873), Gail Taylor (486876), Lakatos, Ferenc, Lakatos, F., Maud Viger, Jennifer DeWoody (486872), Taylor, G., DeWoody, Jennifer, Marinus J M Smulders, Marinus J. M. Smulders (165968), DeWoody, J., Smulders, Marinus JM, Viger, M., Jennifer DeWoody, Tuba, Katalin, Smulders, Marinus J M, Ferenc Lakatos, Taylor, Gail, Lakatos Ferenc, Tuba Katalin, Smulders Marinus J. M., DeWoody Jennifer, Taylor Gail, Viger Maud   +30 more
core   +2 more sources

Born this way: Does variation in perinatal limb bone morphology predict adult locomotor repertoire in primates?

The Anatomical Record, EarlyView.
Abstract Primates show a high degree of locomotor diversity that engenders similar variance in limb bone cross‐sectional geometry and bending strength: leaping primates have stronger hindlimb bones whereas suspensory species have stronger forelimb bones.
Angela M. Mossor, Jeremy Busken, Lorna Benden, Ethan Mardovin, Andrew Bostick, Grégoire Boulinguez‐Ambroise, Timothy D. Smith, Jesse W. Young   +7 more
wiley   +1 more source

Genomic Structural Variations Provide Insights Into Litter Size and Teat Number Traits in Hu Sheep

Animal Research and One Health, EarlyView.
Here, we conducted whole genome sequencing on 300 Hu sheep with an average depth of 16.51X. Two candidate genes associated with litter size and teat number traits were identified, namely MAST2 and AFDN. ABSTRACT Litter size and the teat number are important economic indicators in sheep production.
Xin Xiang, Wei Dai, Jiqiang Liu, Zhengguang Wang   +3 more
wiley   +1 more source

Cross‐Species Single‐Cell Comparative Analysis Reveals Gluconeogenic Features of Hepatocytes in Ruminants

Animal Research and One Health, EarlyView.
In this study, we used cross‐species comparisons to identify ruminant hepatocyte features. We also identified potential genes and TFs involved in coordinating gluconeogenesis in ruminant hepatocytes. By integrating single‐cell data with population genetic analyses, we further identified candidate genetic variation in glucose metabolism and ...
Yaqi Zhou, Wuqiang Huo, Yingran Liu, Yihang Liu, Fei Wang, Tao Shi, Yu Jiang   +6 more
wiley   +1 more source

Genome-Wide Analysis of Tar Spot Complex Resistance in Maize Using Genotyping-by-Sequencing SNPs and Whole-Genome Prediction

The Plant Genome, 2017
Tar spot complex (TSC) is one of the most destructive foliar diseases of maize ( L.) in tropical and subtropical areas of Central and South America, causing significant grain yield losses when weather conditions are conducive.
Shiliang Cao, Alexander Loladze, Yibing Yuan, Yongsheng Wu, Ao Zhang, Jiafa Chen, Gordon Huestis, Jingsheng Cao, Vijay Chaikam, Michael Olsen, Boddupalli M. Prasanna, Felix San Vicente, Xuecai Zhang   +12 more
doaj   +1 more source

Detection of growth-related QTLs in turbot (Scophtalmus maximux) [PDF]

, 2011
Background The turbot (Scophthalmus maximus) is a highly appreciated European aquaculture species. Growth related traits constitute the main goal of the ongoing genetic breeding programs of this species. The recent construction of a consensus linkage map
Toro Ibañez, Miguel Angel, Hermida, Miguel, Fernandez, Jesus, Cerna, Alex, Sanchez Molano, Enrique, Pardo, Belen G., Cabaleiro, Santiago, Bouza, Carmen, Martinez, Paulino   +8 more
core  

Genetic and Population Analyses Implicate Thyroid‐Related Regulation of RNF144B in Chondrocalcinosis

Arthritis &Rheumatology, EarlyView.
Objective Chondrocalcinosis, characterized by calcium crystal deposition within articular cartilage, affects 5% to 15% of the general population and has recently been identified as an osteoarthritis risk factor. However, its biologic pathways remain unclear.
Yahong Wu, Yanning Xu, Paul C. Okoro, Sirine Saafi, Jard de Vries, Xiaoyi Qi, Edwin H. G. Oei, Sita Bierma‐Zeinstra, Trudy Voortman, David Felson, Joyce B. J. van Meurs, Layal Chaker, J. Mark Wilkinson, Michelle S. Yau, Jessica Bertrand, Cindy G. Boer   +15 more
wiley   +1 more source