Tools for quantitative trait locus mapping and genome-wide association study mapping: a review
One of the key objectives in genomics studies is to understand genetic architecture of complex traits and diseases. Quantitative trait locus (QTL) mapping and genome-wide association study (GWAS) mapping have been using to dissect genetic architecture of
Md. Mamun Monir, Zhu Jun
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Multiple QTL for horticultural traits and quantitative resistance to Phytophthora infestans linked on Solanum habrochaites chromosome 11. [PDF]
Previously, a Phytophthora infestans resistance QTL from Solanum habrochaites chromosome 11 was introgressed into cultivated tomato (S. lycopersicum). Fine mapping of this resistance QTL using near-isogenic lines (NILs) revealed some co-located QTL with ...
Haggard, J Erron +2 more
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Effects of the number of markers per haplotype and clustering of haplotypes on the accuracy of QTL mapping and prediction of genomic breeding values [PDF]
The aim of this paper was to compare the effect of haplotype definition on the precision of QTL-mapping and on the accuracy of predicted genomic breeding values.
Mario PL Calus +28 more
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Identification of unconditional and conditional QTL for oil, protein and starch content in maize
Oil, protein and starch are key chemical components of maize kernels. A population of 245 recombinant inbred lines (RILs) derived from a cross between a high-oil inbred line, By804, and a regular inbred line, B73, was used to dissect the genetic ...
Yuqiu Guo +6 more
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Background Teosinte ear bears single spikelet, whereas maize ear bears paired spikelets, doubling the number of grains in each cupulate during maize domestication. In the past 20 years, genetic analysis of single vs.
Zhengjie Chen +9 more
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Quantitative trait loci for bone traits segregating independently of those for growth in an F-2 broiler X layer cross [PDF]
An F broiler-layer cross was phenotyped for 18 skeletal traits at 6, 7 and 9 weeks of age and genotyped with 120 microsatellite markers. Interval mapping identified 61 suggestive and significant QTL on 16 of the 25 linkage groups for 16 traits.
A.S. Law +29 more
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In the past 10 years, interest in applying the tools of molecular genetics to the problem of increasing world rice production has resulted in the generation of two highly saturated, molecular linkage maps of rice, and the localization of numerous genes and quantitative trait loci (QTLs).
S R, McCouch, R W, Doerge
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In the past 15 years, the quantitative trait locus (QTL) mapping approach has been applied to crosses between different inbred mouse strains to identify genetic loci associated with plasma HDL cholesterol levels.
Cheryl Ackert-Bicknell +2 more
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Composite Interval Mapping Based on Lattice Design for Error Control May Increase Power of Quantitative Trait Locus Detection. [PDF]
Experimental error control is very important in quantitative trait locus (QTL) mapping. Although numerous statistical methods have been developed for QTL mapping, a QTL detection model based on an appropriate experimental design that emphasizes error ...
Jianbo He +6 more
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Genetic interactions contribute less than additive effects to quantitative trait variation in yeast. [PDF]
Genetic mapping studies of quantitative traits typically focus on detecting loci that contribute additively to trait variation. Genetic interactions are often proposed as a contributing factor to trait variation, but the relative contribution of ...
Albert, Frank W +5 more
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