Results 81 to 90 of about 741 (144)

Desıgn And Evaluatıon Of A Fıxed Dose Combınatıon For The Treatment Of Hypertensıon

, 2018
Bu çalışmanın amacı, hipertansiyon tedavisinde farklı mekanizmalar ile etki gösteren amlodipin ve enalapril etkin maddelerini tablet dozaj şekli halinde içeren Sabit Dozlu Kombinasyon un (SDK) Kalite Tasarımı (QbD) prensiplerine göre ...
Yaşın, Diren Sarısaltık
core  

The use of heat-assisted antigravity drainage method in the two horizontal wells in gas production from the Qilian Mountain permafrost hydrate deposits

, 2014
The occurrence of gas hydrate deposits in the Qinghai-Tibet plateau permafrost (QTPP) were confirmed during the Scientific Drilling Project of Gas Hydrate in Qilian Mountain permafrost (QMP) in 2008-2009.
Li, Bo, Li, Gang, Zhang, Yu, Li, Xiao-Sen, Chen, Zhao-Yang   +4 more
core   +1 more source

FORMULATION DEVELOPMENT AND OPTIMIZATION OF EMPAGLIFLOZIN FILM COATED TABLET USING QUALITY-BY-DESIGN APPROACH

, 2023
Objective: Development of robust and effective oral solid immediate release film coated tablet of empagliflozin using Quality-by-Design (QbD) approach was the objective of present research work.
ATUL PHATAK, VARDHAMAN BAFNA, MAHESH BHADAGALE, LAKAMBARE, SHRADDHA   +3 more
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Defining the Quality Attributes for Tumor-Infiltrating Lymphocyte Medicinal Products

Tumor-infiltrating lymphocyte (TIL) medicinal products (MPs) show promise for treating solid tumors, especially metastatic melanoma, in the clinical trial setting.
Nijenhuis, Cynthia, Haanen, John B.A.G., Lievense, Justin J., Afd Pharmacoepi & Clinical Pharmacology, Pharmacoepidemiology and Clinical Pharmacology, Beijnen, Jos H., Jonker-Hoogerkamp, Arendien, Jedema, Inge, Moyers, Justin T., Hamid, Omid, Nuijen, Bastiaan   +10 more
core  

Quality by Design: Concept to Applications

, 2019
Background: Quality by Design (QbD) is associated with a modern, systematic, scientific and novel approach which is concerned with pre-distinct objectives that not only focus on product, process understanding but also lead to process control.
Suryakanta Swain, Rabinarayan Parhi, Bikash Ranjan Jena, Sitty Manohar Babu   +3 more
core   +1 more source

Quality by Design (QbD)-Based Regulatory Dossier Preparation of Imiglucerase: A Review

The concept of Quality by Design (QbD) enables the incorporation of scientific knowledge and risk management during the development of drugs. Imiglucerase is a recombinant biological enzyme that serves in the treatment of Type 1 Gaucher disease and thus ...
Shilpa Pise, Harshada R. Khade
core   +1 more source

Intranasal Ion-Triggered In Situ Delivery System of Virus-like Particles: Development Using the Quality by Design Approach

The rapid growth in the prevalence of infectious diseases requires timely action from drug developers. In recent years, the COVID-19 pandemic has demonstrated the unpreparedness of the population for such emergencies.
Anastasiya V. Belyatskaya, Valeriya M. Kondratieva, Olga I. Stepanova, Irina M. Zubareva, Svetlana I. Kosenkova, Ivan I. Krasnyuk, Elena O. Bakhrushina, Tatyana V. Grebennikova, Iosif B. Mikhel   +8 more
core   +1 more source

Desenvolvimento farmacêutico de um medicamento indicado para o tratamento de contraturas musculares: abordagem Quality by Design

Uma abordagem Quality by Design (QbD) tem sido cada vez mais usada e aconselhada pelas entidades reguladoras da indústria farmacêutica. O objetivo geral deste projeto foi desenvolver comprimidos com ação relaxante muscular, tendo em consideração a ...
Carvalho, Ana Filipa Silvestre
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A Review on QbD-Driven Optimization of Lipid Nanoparticles for Oral Drug Delivery: From Framework to Formulation

International Journal of Nanomedicine
Aulia Fikri Hidayat,1,2,* Yoga Windhu Wardhana,3,* Suwendar Suwendar,2,* Ahmed Fouad Abdelwahab Mohammed,4,* Safwat A Mahmoud,5,* Khaled M Elamin,6,* Nasrul Wathoni3,* 1Doctoral Program of Pharmacy,
Hidayat AF, Wardhana YW, Suwendar S, Mohammed AFA, Mahmoud SA, Elamin KM, Wathoni N   +6 more
doaj  

Introducing the Quality Target Administration (QTAP) Profile for Enteral Feeding Tube Medications. [PDF]

Pharmaceutics
Salunke S, Chan CKA, Hu S.
europepmc   +1 more source