Results 1 to 10 of about 151,662 (178)

Enantioselective total synthesis of putative dihydrorosefuran, a monoterpene with an unique 2,5-dihydrofuran structure

open access: yesBeilstein Journal of Organic Chemistry, 2022
An original synthesis of the structure of dihydrorosefuran, a compound allegedly identified in Artemisia pallens and Tagetes mendocina, has been developed.
Irene Torres-García   +5 more
doaj   +1 more source

Enantioselective Synthesis of a New Non-Natural Gabosine

open access: yesMolecules, 2021
The preparation of a new non-natural gabosine is reported, in which the chirality is transferred from the toluene’s biotransformed metabolite (1R,2S)-3-methylcyclohexa-3.5-diene-1,2-diol.
Maximiliano Colobbio   +2 more
doaj   +1 more source

Removing lead from water with carboxylate dendrimers and magnetic nanoparticles modified with carboxylate dendrimers

open access: yesApplied Water Science, 2023
Contamination of water with heavy metals as lead (Pb2+) is a relevant problematic issue. In this work, we have tested different types of dendritic materials for lead removal from water and further recovery. The systems employed are magnetic nanoparticles
David Rincón-Montón   +5 more
doaj   +1 more source

Binding-driven reactivity attenuation enables NMR identification of selective drug candidates for nucleic acid targets

open access: yesCommunications Chemistry, 2022
NMR spectroscopy could be a robust and reliable method for binding detection in drug discovery, but DNA/RNA targets remain challenging to analyze. Here, the authors explore the perturbation of the ligand reactivity caused by complex formation as a ...
Laura Díaz-Casado   +7 more
doaj   +1 more source

Uso de modelado molecular como herramienta didáctica en el primer curso de grado de Química Orgánica

open access: yesEducación Química, 2018
El primer curso de Química Orgánica (Química Orgánica 101) de la Facultad de Química, Universidad de la República (Montevideo, Uruguay) se dicta para las carreras de Química Farmacéutica, Ingeniería Química, Química, Bioquímica Clínica e Ingeniería en ...
Gustavo Seoane   +9 more
doaj   +1 more source

Synthesis and Modeling of Ezetimibe Analogues

open access: yesMolecules, 2021
Ezetimibe is a well-known drug that lowers blood cholesterol levels by reducing its absorption in the small intestine when joining to Niemann-Pick C1-like protein (NPC1L1).
Mateo M. Salgado   +4 more
doaj   +1 more source

Bile acids: Lipase-catalyzed synthesis of new hyodeoxycholic acid derivatives [PDF]

open access: yes, 2018
In this work we present an efficient, environmentally friendly approach to the synthesis of a series of hyodeoxycholic acid derivatives applying Biocatalysis.
Baldessari, Alicia   +3 more
core   +1 more source

Surfactants. XX. Fatty ω-monoesters of dithíoacetals of sugars

open access: yesGrasas y Aceites, 1995
The preparation of 5-O-lauroyl(myhstoyl, palmitoyl)-D-arabinose ethylendithioacetals, 6-O-lauroyl-D-glucose(D-galactose) ethylendithioacetals and 6-O-decanoyl(lauroyl)-D-mannose ethylendithioacetals is reported.
J. Fernández-Bolaños   +2 more
doaj   +1 more source

Volatiles from Subtropical Convolvulaceae That Interfere with Bacterial Cell-to-Cell Communication as Potential Antipathogenic Drugs [PDF]

open access: yes, 2016
Increasing chronic bacterial infections create an urgent need for new antimicrobial agents or strategies for their control. Targetingvirulence is one of the alternative approaches to find new medicines to treat persistent infections due to bacteria with ...
Arena, Mario Eduardo   +5 more
core   +4 more sources

Chemoenzymatic Synthesis of Triazololactams Structurally Related to Pancratistatin [PDF]

open access: yes, 2017
Four tricyclic lactams that structurally resemble alkaloids with the pancratistatin skeleton were synthetized from bromobenzene by a chemoenzymatic strategy.
Bastida   +48 more
core   +1 more source

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