Results 21 to 30 of about 151,662 (178)
Natural Product Communications, 2011 The total synthesis of natural pterocarpans and analogs is reviewed.
Leticia Jiménez-González +4 more
doaj +1 more source
Derivatives of grindelic acid: from a non-active natural diterpene to synthetic antitumor derivatives [PDF]
, 2013 Using several reactions that include homologations and asymmetric epoxidations as well as Ugi and Huisgen couplings, we generated a small focused library of new derivatives from the labdane-type diterpene grindelic acid. These compounds were evaluated as
Chiaramello, Alejandra Ilda +7 more
core +3 more sources
Molecules, 2022 The first stage of the drug discovery process involves the identification of small compounds with biological activity. Iboga alkaloids are monoterpene indole alkaloids (MIAs) containing a fused isoquinuclidine-tetrahydroazepine ring.
Mariana Pazos +6 more
doaj +1 more source
π‐Enlargement in Porphyrin Macrocycles at Interfaces
Angewandte Chemie, EarlyView.On‐surface synthesis of a 20‐π free‐base expanded porphyrin, by depositing onto a hot Ag(111) substrate an 18‐π free‐base precursor equipped with ‐CF3 functional groups ABSTRACT Porphyrins are essential heteroatomic macrocycles, fundamental to both biological systems and advanced technology.
Ana Barragán +11 more
wiley +2 more sources
Frontiers in Chemistry, 2020 The acidity of Al-SBA-15 materials functionalized by ball milling with several niobium loadings (0. 25–1 wt.%) as well as with several fluorine loadings (by wet impregnation using NH4F as a precursor) was characterized and materials investigated in the ...
Miguel Blanco-Sánchez +6 more
doaj +1 more source
Delivery of Therapeutic Biopolymers Employing Silica-Based Nanosystems
Pharmaceutics, 2023 The use of nanoparticles is crucial for the development of a new generation of nanodevices for clinical applications. Silica-based nanoparticles can be tailored with a wide range of functional biopolymers with unique physicochemical properties thus ...
Zoila Gándara +2 more
doaj +1 more source
Angewandte Chemie, EarlyView.A deep‐red‐excited osmium(II) photosensitizer (Os2) induces immunogenic cell death (ICD) under 740 nm irradiation and triggers robust anti‐tumor immune responses both in vitro and in vivo. ABSTRACT Immunogenic cell death (ICD), which converts tumor cells into their own vaccine, plays a pivotal role in the development of novel anticancer therapies. Here,
Yiyi Zhang +12 more
wiley +2 more sources
Pharmaceutics, 2022 An increase in the world population and its life expectancy, as well as the ongoing concern about our physical appearance, have elevated the relevance of dental implantology in recent decades. Engineering strategies to improve the survival rate of dental
Francesca Accioni +4 more
doaj +1 more source
Aryloxyethyl thiocyanates are potent growth inhibitors of Trypanosoma cruzi and Toxoplasma gondii [PDF]
, 2015 As a part of our project aimed at searching new safe chemotherapeutic agents against parasitic diseases, several compounds structurally related to the antiparasitic agent WC-9 (4-phenoxyphenoxyethyl thiocyanate), which were modified at the terminal ...
Chao, Maria Noelia +7 more
core +1 more source
New Short Strategy for the Synthesis of the Dibenz[b,f]oxepin Scaffold
Molecules, 2013 In this report a short and efficient synthesis of the dibenz[b,f]oxepin framework through intramolecular SNAr and McMurry reactions is described. The diaryl ethers required for the McMurry reaction have been obtained in good yields under microwave ...
David R. R. Moreno +3 more
doaj +1 more source