Results 151 to 160 of about 129,304 (280)

The Embryonic Development of the Cotylean Polyclad Phrikoceros jannetae

open access: yesActa Zoologica, EarlyView.
ABSTRACT Polyclads exhibit distinct developmental modes ranging from direct to indirect development, with several transitional stages also recognised. The existence of an indirect developmental mode in polyclads with a planktonic life history stage in the form of a free‐swimming larva is unique among all free‐living flatworms and makes polyclads a ...
Mehrez Gammoudi   +6 more
wiley   +1 more source

Changes in land‐snail communities and steppe environments in the lower Rhône valley during the Lateglacial–Holocene transition

open access: yesBoreas, EarlyView.
Land snail successions in the lower Rhône valley allow us to reconstruct the postglacial recolonization. From the Lateglacial period onwards, Mediterranean steppe communities appeared. The arrival of forest taxa was significantly delayed by aridity. The question of glacial refugia, both local and distant, primarily concerned Mediterranean species of ...
Frédéric Magnin
wiley   +1 more source

Positive modulation of glucagon‐like peptide 1 (GLP‐1) receptor by endogenous haemorphins with implications in glucose metabolism and diabetes

open access: yesBritish Journal of Pharmacology, EarlyView.
Haemorphins act on GLP‐1 receptor (GLP‐1R) activity and signalling in a positive allosteric manner. This leads to potentiated GLP‐1‐mediated activity and signalling, as well as insulin synthesis, which may have implications for glucose metabolism and, thereby, diabetes and obesity. (The graph was created in BioRender.com).
Farheen Badrealam Khan   +13 more
wiley   +1 more source

Novelty in Creativity and Innovation Management Research: The What and How for Authors and Reviewers

open access: yesCreativity and Innovation Management, EarlyView.
ABSTRACT Novelty is widely regarded as the foundation of scholarly contributions, yet its definition and pathways to achieve novelty remain too open for interpretation, especially for young scholars. This article reviews existing debates on novelty and advances a definition and framework that connects different knowledge production modes to three ...
Paola Bellis   +3 more
wiley   +1 more source

Tillsammans ställer vi om med hjälp av skogen [Elektronisk resurs] : Policybrief II, 2015

open access: yes, 2015
I projektet ”Omställning till bioekonomi, smart specialiseringoch quadruple helix” var ett av målen att skapa förståelse för den fjärde helixen i regionala innovationssystem inom ramen ör en skoglig bioekonomi i Värmland.
Grundel, Ida,
core  

A Biweekly GLP‐1R Agonist Designed With Drug‐Free Intervals for Enhanced Efficacy, Receptor Homeostasis and Gastrointestinal Tolerability

open access: yesDiabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aim To develop a next‐generation, longer‐acting, more‐clinical‐benefits agonist to achieve sustained efficacy with improved tolerability. Methods CT130 was designed from semaglutide. Binding affinity was validated via molecular dynamics and cellular assays.
Wei Ding   +4 more
wiley   +1 more source

Quadruple Helix Collaboration Mapping for Fashion Economic Development in Bandung

open access: yes, 2015
. Quadruple Helix is a system of collaboration between university, industry, government and citizen. Quadruple Helix consists of government as policy maker, university as researcher, industry as economic driver manufacturer plus community as connector ...
Hudani, Hafiz, Dhewanto, Wawan
core  

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