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Quality by Design for the Nanoformulation of Cosmeceuticals [PDF]

open access: yesPharmaceutics
Cosmeceuticals are cosmetic formulations that are intended to alleviate skin conditions that affect its appearance and functionality. They are not considered medications but contain molecules that exert biological action on the skin beyond traditional ...
Gerardo Leyva-Gómez   +6 more
doaj   +2 more sources

Aspects and Implementation of Pharmaceutical Quality by Design from Conceptual Frameworks to Industrial Applications [PDF]

open access: yesPharmaceutics
Background/Objectives: Quality by Design (QbD) has revolutionized pharmaceutical development by transitioning from reactive quality testing to proactive, science-driven methodologies.
Shiwei Yang   +8 more
doaj   +2 more sources

Quality by Design and In Silico Approach in SNEDDS Development: A Comprehensive Formulation Framework [PDF]

open access: yesPharmaceutics
Background/Objectives: The Self-Nanoemulsifying Drug Delivery System (SNEDDS) has been widely applied in oral drug delivery, particularly for poorly water-soluble compounds.
Sani Ega Priani   +4 more
doaj   +2 more sources

Important Aspects of the Design of Experiments and Data Treatment in the Analytical Quality by Design Framework for Chromatographic Method Development [PDF]

open access: yesMolecules
In the analytical quality by design (AQbD) framework, the design of experiments (DOE) plays a very important role, as it provides information about how experimental input variables influence critical method attributes.
Bianca F. G. Passerine   +1 more
doaj   +2 more sources

Quality by Design (QbD)-Driven Development and Optimization of Tacrolimus-Loaded Microemulsion for the Treatment of Skin Inflammation [PDF]

open access: yesPharmaceutics
Background: Skin inflammation represents a hallmark of many skin conditions, from psoriasis to eczema. Here, we present a novel microemulsion formulation for delivering a low dose of potent immunosuppressant, tacrolimus, to the skin for local ...
Sanjida Ahmed Srishti   +5 more
doaj   +2 more sources

Transcriptome analysis identifies key gene LiMYB305 involved in monoterpene biosynthesis in Lilium ‘Siberia’

open access: yesFrontiers in Plant Science, 2022
Lilium is a popular cut flower that is highly favored by consumers due to its snowy white color and strong fragrance, which originates from the release of monoterpenes.
Yun-Yao Yang   +10 more
doaj   +1 more source

Quality by design approach with design of experiment for sample preparation techniques

open access: yesAdvances in Sample Preparation, 2023
The quality by design (QbD) based approach has begun to be embedded in various method development. Studies show that with the design of experiment tool, the analysis process has become more efficient, faster, and easier.
Saniye Özcan   +2 more
doaj   +1 more source

Quality-by-Design-Based Development of a Voxelotor Self-Nanoemulsifying Drug-Delivery System with Improved Biopharmaceutical Attributes

open access: yesPharmaceutics, 2021
Low aqueous solubility and poor oral bioavailability are limiting factors in the oral delivery of voxelotor, an antisickling agent. To overcome these limitations, a voxelotor self-nanoemulsifying drug delivery system was developed.
Aristote B. Buya   +6 more
doaj   +1 more source

Risk-Assessment-Based Optimization Favours the Development of Albumin Nanoparticles with Proper Characteristics Prior to Drug Loading

open access: yesPharmaceutics, 2022
Albumin nanocarrier research and development is a challenging area in the field of personalized medicine and in providing advanced therapeutic solutions.
Gábor Katona   +2 more
doaj   +1 more source

Understanding barriers and benefits to adopting elephant coexistence practices in oil palm plantation landscapes in Lower Kinabatangan, Sabah

open access: yesFrontiers in Conservation Science, 2022
Oil palm managers are one of the key stakeholders who could help strengthen efforts to protect elephants in the landscape. We used a Theory of Change (ToC) approach to hypothesize potential barriers and benefits to managers adopting best practise.
Nurzhafarina Othman   +4 more
doaj   +1 more source

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