Results 221 to 230 of about 24,758,777 (295)

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

open access: yesFEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada   +5 more
wiley   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

open access: yesFEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth   +6 more
wiley   +1 more source

Glossary and tables for statistical quality control

open access: yes, 1983
American Society for Quality Control
core  

Mitochondrial quality control mechanisms as therapeutic targets in doxorubicin-induced cardiotoxicity.

TIPS - Trends in Pharmacological Sciences, 2022
Doxorubicin (DOX) is a chemotherapeutic drug that is utilized for solid tumors and hematologic malignancies, but its clinical application is hampered by life-threatening cardiotoxicity including cardiac dilation and heart failure.
Lin Wu   +4 more
semanticscholar   +1 more source

Mitochondrial quality control in health and in Parkinson's disease.

Physiological Reviews, 2022
As a central hub for cellular metabolism and intracellular signalling, the mitochondrion is a pivotal organelle, dysfunction of which has been linked to several human diseases including neurodegenerative disorders, and in particular Parkinson's disease ...
Mohamed A. Eldeeb   +4 more
semanticscholar   +1 more source

Quality Control

AI and Big Data in Cardiology, 2023
Conventional models of voting behavior depict individuals who judge governments for how the world unfolds during their time in office. This phenomenon of retrospective voting requires that individuals integrate and appraise streams of performance ...
Ilkay Öksüz   +2 more
semanticscholar   +1 more source

Contamination issues as a challenge in quality control and quality assurance in microplastics analytics.

Journal of Hazardous Materials, 2021
Microplastics are widely distributed environmental contaminants. To understand their impacts on the environment and health, more high-quality results are needed.
J. C. Prata   +5 more
semanticscholar   +1 more source

Quality Control and Quality Assurance

Clinics in Laboratory Medicine, 1986
The office laboratory's need for quality is no different from that of any other clinical laboratory. If patients are to receive the benefit of physician's office testing, reliable, high-quality laboratory results are essential. To achieve this, the physician's office laboratory must have an adequate quality assurance program.
R H, Laessig   +2 more
openaire   +2 more sources

Controlling the Cost of Quality Control

Clinics in Laboratory Medicine, 1986
In the present era of expanding technology coexisting with economic constraint, appropriate quality control criteria to monitor laboratory performance must take into consideration not only analytic precision and medical utility, but also cost effectiveness.
J, Woo, R S, Schifreen, J W, Winkelman
openaire   +2 more sources

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