Results 231 to 240 of about 9,335,776 (306)

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

FEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li, Xi Xiao, Lingbin Qi, Chanyi Li, Sirui Song, Jiaying Qin, Zhigang Xue, Jinfeng Xue, Huaifang Li   +8 more
wiley   +1 more source

Diagnostic accuracy of SPECT/CT in parathyroid adenoma detection: impact of radiopharmaceutical choice and quality control practices. [PDF]

EJNMMI Rep
Alasmari B, Sherif RSE, Ghannam MM, Elsaban K, Al-Amri MA.   +4 more
europepmc   +1 more source

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

FEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand, Paulina Lau, Ruth McPherson   +2 more
wiley   +1 more source

Quality Assurance/Quality Control

, 2018
openaire   +2 more sources

Mitochondrial Quality Control and Metabolic Reprogramming in Hepatocellular Carcinoma: Implications for Immunotherapy and Treatment Resistance. [PDF]

Cells
Zarlashat Y, Picca A.
europepmc   +1 more source

Alcohol‐induced altered glycans in human tracheal epithelial cells promote bacterial adhesion

FEBS Open Bio, EarlyView.
Alcohol induces altered glycans to promote bacteria adhesion. Heavy alcohol drinking is known to increase the risk of bacterial pneumonia. However, the link between alcohol levels and risk of infection remains underexplored. Recently, we found that alcohol induced α2‐6sialo mucin O‐glycans in human tracheobronchial epithelial cells, which mediated the ...
Pi‐Wan Cheng, Souvik Datta, Derrick R. Samuelson   +2 more
wiley   +1 more source

Turnover of missense mutant cytosolic proteins proceeds in the absence of major quality control E3 ligases. [PDF]

MicroPubl Biol
Baker HA, Grall-Johnson C, Budzyńska PM, Kim J, Mayor T.   +4 more
europepmc   +1 more source

TANK-binding kinase 1 protects against MASH progression via mitochondrial quality control. [PDF]

Exp Mol Med
An SM, Jang JH, Sung JH, Myung JW, Jeon YG, Lee WT, Jeon JW, Yim KM, Lee JH, Zhang B, Seo JB, Im SS, Kim JB, Saltiel AR, Huh JY.   +14 more
europepmc   +1 more source