Results 121 to 130 of about 13,484,742 (306)
FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
Quality Improvement Division Operational Plan 2017
, 2017 The Quality Improvement Division provides advice and support quality improvement projects and initiatives. We do this by partnering with frontline services however the implementation of these programmes remains with the leadership of frontline ...
Quality Improvement Division
core
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
New Evidence on Product Quality and Trade [PDF]
This paper examines why different countries export different qualities of products.Previous studies have attributed quality dispersion to differences in factor endowments while no empirical work has been done examining the effect of technology on quality.
Hasan Faruq
core
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
National Quality Improvement Team Annual Report 2017
, 2018 This report is a high level overview of work completed by the National Quality Improvement Team (formerly known as the Quality Improvement Division) in 2018.
National Quality Improvement Team
core
CeramicsIn this study, we used solid-state synthesis to prepare Ba[(ZnxCo1−x)1/3(Nb0.5Ta0.5)2/3]O3 microwave ceramics for mobile communications. Compared with Ba[Zn1/3(Nb0.5Ta0.5)2/3]O3, in the prepared materials, Co2+ substitution with Zn2+ improved the Q × f ...
Yuan-Bin Chen +3 more
doaj +1 more source
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source