Results 121 to 130 of about 2,615,956 (315)
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
Quality of information as strategic factor in Accounting Information System (AIS) towards better organizational performance [PDF]
The aim this study is to examine the information quality and its effect on performance of Iraqi companies.Organizations were found aware on the need to organizations agree on the importance of accounting information system (AIS) as to gather, perform ...
Mohammed Sami +2 more
core
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
The Quality Traits of Pork Belly and Impact Factors of Quality
Pork belly is one of the most valuable primal cuts of pork with high preferences. Although meat quality is becoming increasingly important, defining pork belly quality is challenging owing to the structure and diversity of the preferred characteristics. This study identified the factors influencing pork belly quality traits through a literature review.
Kyung Jo +6 more
openaire +2 more sources
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
Computer-assisted approaches to the collection of quality of life data in oncology [PDF]
The assessment of cancer patients' quality of life (QOL) has been increasing in both importance and relevance in recent years, and is becoming more integrated into clinical practice.
Smith, Adam Barnett +1 more
core
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
The Long and Short (of) Quality Ladders [PDF]
Prices are typically used as proxies for countries' export quality. I relax this strong assumption by exploiting both price and quantity information to estimate the quality of products exported to the U.S.
Amit Khandelwal
core

