Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
FEBS Letters, EarlyView.Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
A hybrid Data Quality Indicator and statistical method for improving uncertainty analysis in LCA of a small off-grid wind turbine [PDF]
, 2014 In Life Cycle Assessment (LCA) uncertainty analysis has been recommended when choosing sustainable products. Both Data Quality Indicator and statistical methods are used to estimate data uncertainties in LCA.
Cheung, Wai Ming +3 more
core
Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
FEBS Letters, EarlyView.The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
Early mortality after chemotherapy as a quality indicator-the leukemia perspective. [PDF]
Blood Cancer J, 2023 Kantarjian H, Welch MA, Sasaki K.
europepmc +1 more source
Prescription of paracetamol-containing medications as indicator of quality of prescribing [PDF]
, 2007 Batty, Gwenno M. +6 more
core +1 more source
Clinical indicators of quality for Australian residential aged care facilities : establishing reliability, validity, and quality thresholds [PDF]
, 2010 Background: In response to the need for more comprehensive quality assessment within Australian residential aged care facilities, the Clinical Care Indicator (CCI) Tool was developed to collect outcome data as a means of making inferences about quality ...
O'Reilly, Maria Therese
core +1 more source
FEBS Letters, EarlyView.This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
Assessment of Pancreatic Cancer Care in the United States Based on Formally Developed Quality Indicators [PDF]
, 2009 Karl Y. Bilimoria +4 more
openalex +1 more source
Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
FEBS Letters, EarlyView.Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
Quality indicators and community pharmacy services: a scoping review [PDF]
, 2019 Nour Alhusein, Margaret Watson
openalex +1 more source