Results 141 to 150 of about 20,259,607 (299)

Quality Assurance Policies and Indicators for Long-Term Care in the European Union. Country Report: Latvia. ENEPRI Research Report No. 108, March 2012 [PDF]

, 2012
This paper describes the quality assurance system for long-term care services in Latvia. Policy planning for long-term care is undertaken by the Ministry of Welfare and the municipalities.
Plakane, Baiba
core  

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

A new set of quality indicators for palliative care: process and results of the development trajectory

, 2011
CONTEXT: In some countries (the United States in particular), quality indicators for palliative care have already been developed. However, these quality indicators often cover one specific setting or target group, for example, palliative cancer care or ...
Hella E. Belarbi, Francke, A.L., Claessen, Susanne JJ, Deliens, L., Belarbi, H.E., Belarbi, Hella E, Anneke L. Francke, Claessen, S.J.J., Pasman, H.R.W., Pasman, H Roeline W, van der Putten, Marianne JA, Deliens, Luc, van der Putten, M.J.A., H. Roeline W. Pasman, Luc Deliens, Susanne J.J. Claessen, Marianne J.A. van der Putten, Francke, Anneke L, Putten, M.J.A. van der   +18 more
core   +1 more source

Factors associated with the performance and achieving goals of specialized periodontal procedures in Brazilian dental specialties centers

BMC Health Services Research
Background The Brazilian Dental Specialty Centers (CEO, in Portuguese) represent the strategy of the National Oral Health Policy to provide secondary-level dental care. They offer more complex procedures, such as the treatment of periodontitis.
Raíres Chaves da Silva Rodrigues, Yuri Wanderley Cavalcanti, Edson Hilan Gomes de Lucena   +2 more
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

COVID-19 Database of public health guidance - 12 November 2021

, 2021
To inform the ongoing response to the COVID-19 pandemic, specifically, to inform the development of public health guidance to prevent the spread of COVID-19, we have created a database of COVID-19 public health guidance produced by international ...
Health Information and Quality Authority (HIQA)
core  

[Spirometry in a health care center: indications, results and quality.].

Laeknabladid, 2015
Spirometry is important for the diagnosis and treatment of lung diseases. Studies on the use of spirometry in health care centers are few and none in Iceland. The objective of this study was to evaluate the use of spirometry in a single health care center in Iceland in regard to indications, quality and results.Patients evaluated at the Primary Care ...
Gunnar, Guðmundsson, Sólveig Dóra, Magnúsdóttir, Jón Steinar, Jónsson   +2 more
openaire   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

Healthy Futures—Aboriginal Community Controlled Health Services: report card [PDF]

, 2015
During 2012-13, Aboriginal Community Controlled Health Services saw just over 250,000 Indigenous clients. This report shows increases in the proportion of clients receiving appropriate processes of care for ten of the 16 primary health care indicators ...
Australian Institute of Health and Welfare
core  

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source