Results 121 to 130 of about 353,246 (310)

Patient experiences with interdisciplinary treatment for substance dependence: an assessment of quality indicators based on two national surveys in Norway

Patient Preference and Adherence, 2019
Mona Haugum,1,2 Hilde Hestad Iversen,1 Jon Helgeland,1 Anne Karin Lindahl,2,3 Oyvind Bjertnaes11Division of Health Services, Norwegian Institute of Public Health, Oslo, Norway; 2Department of Health Management and Health Economics, Institute of Health ...
Haugum M, Iversen HH, Helgeland J, Lindahl AK, Bjertnaes O   +4 more
doaj  

Associations between length of stay in long term care facilities and end of life care. Analysis of the pace cross-sectional study

, 2020
Long term care facilities (LTCFs) are increasingly a place of care at end of life in Europe. Longer residence in an LTCF prior to death has been associated with higher indicators of end of life care; however, the relationship has not been fully explored.
Deliens, L., Onwuteaka-Philipsen, B., Smets, Tinne, Kijowska, V., Gambassi, G, Kylänen, M., Gambassi, Giovanni, Payne, S, Van den Block, Lieve, Sheila Payne, Lieve Van den Block, Keegan, Thomas, Marika Kylänen, Violetta Kijowska, Danni Collingridge Moore, Kijowska, V, Moore, D.C., Thomas Keegan, Bregje Onwuteaka-Philipsen, Kylanen, Marika, Gambassi, G., Deliens, Luc, Payne, Sheila, Kijowska, Violetta, Luc Deliens, Payne, S., Keegan, T., Keegan, T, Onwuteaka-Philipsen, Bregje, Tinne Smets, Moore, Danni Collingridge, Kylänen, M, Smets, T., Giovanni Gambassi, Onwuteaka-Philipsen, B, Collingridge Moore, D, Van den Block, L.   +36 more
core   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

Health at a glance 2013: OECD indicators [PDF]

, 2013
This publication provides the latest comparable data on different aspects of the performance of health systems in OECD countries. It provides striking evidence of large variations across countries in the costs, activities and results of health ...

core  

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Quality Indicators for Transition from Pediatric to Adult Care for Youth With Chronic Conditions: Proposal for an Online Modified Delphi Study

JMIR Research Protocols
BackgroundThe transition from pediatric to adult care poses a significant health system–level challenge impeding the delivery of quality health services for youth with chronic health conditions.
Alene Toulany, Dmitry Khodyakov, Sarah Mooney, Lisa Stromquist, Katherine Bailey, Claire EH Barber, Michelle Batthish, Kristin Cleverley, Gina Dimitropoulos, Jan Willem Gorter, Danijela Grahovac, Ruth Grimes, Beverly Guttman, Michèle L Hébert, Tomisin John, Lisha Lo, Dorothy Luong, Laura MacGregor, Geetha Mukerji, Jacklynn Pidduck, Vjura Senthilnathan, Rayzel Shulman, Patricia Trbovich, Sarah EP Munce   +23 more
doaj   +1 more source

[Health care model and quality indicators: perceptions of primary health care professionals].

Cadernos de saude publica, 2011
This study aimed to verify the adequacy of family health teams according to the quality standards set by the Brazilian Ministry of Health and the correlation with health care activities, according to the health professionals themselves. The Evaluation for Quality Improvement (EQI) instrument was used in joint interviews with physicians, nurses, and ...
José Mendes da, Silva, Antônio Prates, Caldeira   +1 more
openaire   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Quality indicators for deceased organ and tissue donation for transplantation: a scoping review protocol

Systematic Reviews
Background The global shortage of organs and tissues highlights the need to strengthen and monitor the quality of deceased donor programs. Evaluating each stage of this process using quality-sensitive indicators is essential to ensure transparency ...
Rafael Rodrigo da Silva Pimentel, Daisy Maria Rizatto Tronchin, Marcelo José dos Santos, Maristela Santini Martins, Ágata Nunes Brito, Fabiana Lopes Pereira Santana   +5 more
doaj   +1 more source