Results 101 to 110 of about 93,126 (196)

Beyond digital twins: the role of foundation models in enhancing the interpretability of multiomics modalities in precision medicine

open access: yesFEBS Open Bio, EarlyView.
This review highlights how foundation models enhance predictive healthcare by integrating advanced digital twin modeling with multiomics and biomedical data. This approach supports disease management, risk assessment, and personalized medicine, with the goal of optimizing health outcomes through adaptive, interpretable digital simulations, accessible ...
Sakhaa Alsaedi   +2 more
wiley   +1 more source

Hydrophobicity causes anomalous migration of cystine/glutamate antiporter SLC7A11 in SDS‐PAGE with low acrylamide concentration

open access: yesFEBS Open Bio, EarlyView.
SLC7A11 frequently migrates faster in SDS‐PAGE. The present study found that the high hydrophobicity of SLC7A11 causes its anomalous migration in SDS‐PAGE with a low concentration of acrylamide gel. Replacing isoleucine with asparagine reduced hydrophobicity and restored its normal migration at 55 kDa, revealing the role of hydrophobicity and gel ...
Nsengiyumva Emmanuel   +13 more
wiley   +1 more source

An integrated sustainable QMS framework for the South African packaging industry

open access: yesSouth African Journal of Business Management
Purpose: This paper explores the influence of ISO 9001:2015 certification on business performance in the packaging industry in South Africa. Additionally, the study proposes a comprehensive and sustainable quality management system (QMS) framework that ...
Raveen Rathilall   +2 more
doaj   +1 more source

Quality management

open access: yes, 2019
Quality management proposal for the W-STEM Capacity-Building project (Ref. 598923-EPP-1-2018-1-ES-EPPKA2-CBHE-JP) presented in the kick-off meeting in Salamanca (Spain) on 25-27 March 2019.
openaire   +2 more sources

Comparative single‐cell transcriptomic profiling of patient‐derived renal carcinoma cells in cellular and animal models of kidney cancer

open access: yesFEBS Open Bio, EarlyView.
We generated and characterized clear cell renal cell carcinoma models using the patient‐derived RCC243 cell line—including cell culture, orthotopic, and metastatic tumors—via single‐cell RNA‐sequencing for comparisons between models and patient tumor datasets.
Richard Huang   +9 more
wiley   +1 more source

Long non‐coding RNAs as therapeutic targets in head and neck squamous cell carcinoma and clinical application

open access: yesFEBS Open Bio, EarlyView.
Long non‐coding RNAs (lncRNAs) occupy an abundant fraction of the eukaryotic transcriptome and an emerging area in cancer research. Regulation by lncRNAs is based on their subcellular localization in HNSCC. This cartoon shows the various functions of lncRNAs in HNSCC discussed in this review.
Ellen T. Tran   +3 more
wiley   +1 more source

Understanding and Overcoming Immunotherapy Resistance in Skin Cancer: Mechanisms and Strategies

open access: yesAging and Cancer, EarlyView.
This narrative review explores the mechanisms driving immunotherapy resistance in skin cancer, including tumor microenvironment factors, genetic mutations, and immune evasion strategies. It highlights potential strategies to overcome resistance, offering insights for improving therapeutic outcomes and guiding future research in personalized ...
Shreya Singh Beniwal   +8 more
wiley   +1 more source

Prevalence of sleep disturbances in endometriosis patients: a systematic review and meta-analysis

open access: yesFrontiers in Psychiatry
ObjectiveThis study systematically analyzes the prevalence of sleep disturbance in patients with endometriosis.MethodsThe PubMed, Web of Science, Embase, Wanfang, China National Knowledge Internet Database (CNKI), China Science and Technology Journal ...
Yujie Zhang   +4 more
doaj   +1 more source

Data Quality Management

open access: yes, 2019
Data quality is crucial in measuring and analyzing science, technology and innovation adequately, which allows for the proper monitoring of research efficiency, productivity and even strategic decision making. In this chapter, the concept of data quality will be defined in terms of the different dimensions that together determine the quality of data ...
openaire   +4 more sources

Study on the benefit analysis based on whole life cycle carbon emission calculation after the construction of photovoltaic systems in macau's construction waste landfills

open access: yesScientific Reports
This study seeks to assess both environmental and economic effects associated with installing photovoltaic systems within construction waste landfills in Macau by employing an effective carbon emissions calculation methodology and benefit analysis method.
Zhaobin Li   +5 more
doaj   +1 more source

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