Results 111 to 120 of about 20,858,356 (406)
A subset of MMR‐proficient colon cancers responds to neoadjuvant immunotherapy
Tan et al. reveal that a distinct subset of early‐stage pMMR colon cancers can respond to neoadjuvant immunotherapy. In the NICHE‐2 trial, responders (26%) were characterized by chromosomal instability, TP53 mutations, and proliferative cell‐cycle programs, whereas nonresponders showed metabolic and stromal reprogramming with TGF‐β‐driven ...
Eleonora Piumatti +3 more
wiley +1 more source
The effects of ground cover management on fruit yield and quality: a meta-analysis
Linfa Fang +6 more
openalex +2 more sources
Quality Management System pada PT. X [PDF]
Penelitian ini bertujuan untuk menganalisa Quality Management System pada aspek struktur, sistem dan budaya Perusahaan PT. X. Penelitian ini akan dilaksanakan dengan menyebarkan kuesioner kepada responden karyawan PT.
Soetanto, I. (Iwan)
core
This study optimizes a two‐step induction system to generate PGCLCs from chicken ESCs. The induced cells express germline markers and migrate to gonads in ovo, offering a novel approach for avian genetic resource conservation. Primordial germ cells (PGCs) are the progenitor cells of sperm and eggs.
Zeyu Li +10 more
wiley +1 more source
T HE CARE and treatment of the cancer patient is a highly complex activity. Multiple professional staff and family members are involved. Physicians and staff from several organizations may contribute to the overall care plan for the patient. Different professionals each have their role.
openaire +2 more sources
Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini +2 more
wiley +1 more source
Improved quality and disease management in diverse populations [PDF]
Improved biodiversity is one of the key principles in organic farming and therefore organic plant breeding seeks alternatives to the currently dominant pureline monocultures.
Borgen, Anders
core
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan +6 more
wiley +1 more source

