Results 91 to 100 of about 4,051,688 (392)
Multi‐omics profiling reveals key factors involved in Ewing sarcoma metastasis
Molecular Oncology, EarlyView.Using a mouse model that recapitulates the spread of tumor cells within the body, we have profiled paired tumors and metastasis samples using a multiomics approach combining different layers of biological information. We identified key genes that drive metastasis in Ewing sarcoma.
Mariona Chicón‐Bosch +11 more
wiley +1 more source
Frontiers in Pain Research, 2022 BackgroundOpioids have been commonly used to treat chronic pain, but they are associated with significant morbidity and mortality. Cannabis has been advocated as an alternative; however, a growing number of patients are now using a combination of opioid ...
Vafi Salmasi +3 more
doaj +1 more source
World Journal of Gastroenterology, 2019 BACKGROUND Inflammatory bowel diseases (IBD) have been associated with a low quality of life (QoL) and a negative impact on work productivity compared to the general population.
R. Parra +29 more
semanticscholar +1 more source
Patient and health care professional decision-making to commence and withdraw from renal dialysis: A systematic review of qualitative research [PDF]
, 2015 Background and objectives. To ensure decisions to start and stop dialysis in end stage kidney disease are shared, the factors that affect patients and healthcare professionals in making such decisions need to be understood. This systematic review aims to
Flemming, K. +8 more
core +1 more source
Molecular Oncology, EarlyView.Triacsin C inhibition of the acyl‐CoA synthetase long chain (ACSL) family decreases multiple myeloma cell survival, proliferation, mitochondrial respiration, and membrane potential. Made with Biorender.com. Multiple myeloma (MM) is an incurable cancer of plasma cells with a 5‐year survival rate of 59%.
Connor S. Murphy +12 more
wiley +1 more source
Molecular Oncology, EarlyView.FOXL2 c.402C>G mutation drives granulosa cell tumors. Using CRISPR technology, we selectively corrected this mutation, reducing malignancy and increasing sensitivity to dasatinib and ketoconazole. Transcriptomic changes revealed potential therapeutic targets, demonstrating CRISPR's promise for treating this rare ovarian cancer.
Sandra Amarilla‐Quintana +17 more
wiley +1 more source
A Cross- Sectional Study on the Quality of Life of Healthcare Professionals
Haseki Tıp Bülteni, 2011 Aim: Today, the work environment is one of the factors affecting the quality of life. Indeed, in a stressful environment, health care providers must work carefully and diligently. In this study, we aimed to determine health workers’ perception towards
Abdulkadir Ergen +2 more
doaj
Cognizance of Post-COVID-19 Multi-Organ Dysfunction through Machine Learning Analysis [PDF]
arXiv, 2023 In the year 2022, a total of 466 patients from various cities across Iraq were included in this study. This research paper focuses on the application of machine learning techniques to analyse and predict multi-organ dysfunction in individuals experiencing Post-COVID-19 Syndrome, commonly known as Long COVID. Post-COVID-19 Syndrome presents a wide array
arxiv
Quality of Life, Public Services and the Crisis [PDF]
, 2013 This issue of Foundation Focus looks at impacts of the crisis on quality of life in Europe. Has quality of life worsened? Have all sections of society borne the impact equally, or have some ill-favoured groups been particularly affected?
Eurofound
core +1 more source
Molecular Oncology, EarlyView.TOMM20 increases cancer aggressiveness by maintaining a reduced state with increased NADH and NADPH levels, oxidative phosphorylation (OXPHOS), and apoptosis resistance while reducing reactive oxygen species (ROS) levels. Conversely, CRISPR‐Cas9 knockdown of TOMM20 alters these cancer‐aggressive traits.
Ranakul Islam +9 more
wiley +1 more source