Results 81 to 90 of about 168,723,046 (286)

Are healthcare organizations healthy? Quality of life in healthcare work in Northern and Southern Europe

Sociologia, Problemas e Práticas, 2017
From a gender perspective, this article analyses the concept of “healthy organization” through the study of the “dual agenda” of healthcare organizations. Based in the EU funded project “Quality of Life in a Changing Europe”, which priviledged a multi-method approach, we analyse data from an extensive survey applied in eight European countries (Germany,
Bäck-Wiklund, Margareta, Guerreiro, Maria das Dores, Szücs, Stefan, Billquist, Leila, Barroso, Margarida Martins, Rodrigues, Eduardo Alexandre   +5 more
openaire   +4 more sources

Predictive and prognostic biomarkers of Bacillus Calmette‐Guérin therapy failure in bladder cancer patients: A systematic review

Molecular Oncology, EarlyView.
High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira, Ana Teixeira‐Marques, Rui Freitas, João A Carvalho, Sara Monteiro‐Reis, Giorgio I. Russo, Rui Henrique, Carmen Jerónimo   +7 more
wiley   +1 more source

Patient led PROMs must take centre stage in cancer research

Research Involvement and Engagement, 2018
Plain English summary Patient involvement in research is about adding value rather than commenting on technical quality. After 15 years as an involved patient in cancer research I started looking around and I found I was asking myself, where is the next ...
Roger Wilson
doaj   +1 more source

Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation

Molecular Oncology, EarlyView.
How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim, Alvin Kunyao Guo, Yoko Itahana, Srinivasaraghavan Kannan, Valerie Goh, Mingmin Ong, Terina Yan Wen Tay, Weiying Ye, Sabhashina Radha Krishnan, Jun Nishiyama, Chandra S Verma, Koji Itahana   +11 more
wiley   +1 more source

Engineering IL‐4 resistant proinflammatory human myeloid cells for cancer immunotherapy

Molecular Oncology, EarlyView.
We developed a scalable workflow to generate proinflammatory human myeloid cells. CRISPR/Cas9‐edited CD34+ hematopoietic stem and progenitor cells were expanded and differentiated with M‐CSF. Deletion of STAT6 or STAT6/NFKB1 enhanced macrophage proinflammatory gene expression and cytokine secretion in the presence of IL‐4 while maintaining antibody ...
Theresa Barberi, Alan D. Friedman
wiley   +1 more source

Long-term health-related quality of life, healthcare utilisation and back-to-work activities in intensive care unit survivors: Prospective confirmatory study from the Frisian aftercare cohort. [PDF]

PLoS One, 2022
Beumeler LFE, van Wieren A, Buter H, van Zutphen T, Navis GJ, Boerma EC.   +5 more
europepmc   +1 more source

Compassion and the quality of life of the inpatient healthcare team

European Psychiatry
Introduction Nurse-patient relationships and interactions during inpatient care evoke feelings of empathy and compassion. Compassion can lead to satisfaction, but also to exhaustion. Compassion fatigue is a commonly used concept that signifies the exhaustion of healthcare personnel due to the specific activities and repeated exposure to the suffering ...
A.-C. Bredicean, C. Giurgi-Oncu, L. Palaghian, D. Tabugan, A. Neagu, G. Covaci, R. Homeag, S. Ursoniu   +7 more
openaire   +2 more sources

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

FEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell, Cassy Ross, Panagiota S. Filippou, Bruno Silvester Lopes, Dominic Gilchrist, Paul Dean, Kamar Ameen‐Ali, Tora K. Smulders‐Srinivasan, Ahmad A. Khundakar   +8 more
wiley   +1 more source

Investigation of quality of work life and its relationship with job performance in health care workers

Muhandisī-i bihdāsht-i ḥirfah/ī, 2017
Introduction: Healthcare centers are one of main organizations which play important role in maintaining people s health by providing healthcare services. Therefore, paying attention to quality of work life (QWL) & job performance in healthcare workers is
Ehsan Bakhshi, Reza Kalantari
doaj  

Association between diet and quality of life among healthcare professionals in King Saud University Medical City

Frontiers in Public Health
BackgroundA balanced diet and active lifestyle are key factors influencing health and quality of life (QoL). This study examined the relationships between eating patterns, physical activity, and QoL among Arab healthcare professionals.MethodologyA cross ...
Waad Alfawaz, Reem S. Albassam, Noura Almuharib, Shuruq Alghafis, Walaa Mahfouz   +4 more
doaj   +1 more source