Relação entre dor crônica e atividade laboral em pacientes portadores de síndromes dolorosas
Revista DorJUSTIFICATIVA E OBJETIVOS: O presente estudo objetivou identificar a influência da dor crônica no prejuízo da atividade laboral de pacientes atendidos no Serviço de Dor Crônica do Hospital Universitário da Universidade Federal do Maranhão.
Beatriz Tavares Garcia +2 more
doaj +1 more source
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Quality of working life of employees in public healthcare organization in Finland: A cross-sectional study. [PDF]
Nurs Open, 2023 Kesti R +3 more
europepmc +1 more source
FEBS Letters, EarlyView.The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
Extending working life in Belgium. CEPS Working Document No. 386, 22 November 2013 [PDF]
, 2013 This report aims at understanding how persons aged 50 years and older are and can be integrated into the working society in Belgium. We are interested in how people in this age group can be induced to engage in various forms of employment and lifelong ...
Marttellucci, Elisa +2 more
core
The quality of working life: gap between perception and idealization impact of gender and status. [PDF]
Front Psychol, 2023 Salès-Wuillemin E +4 more
europepmc +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Institutionalisation and Quality of Life for Elderly People in Finland. ENEPRI Research Report No. 92, August 2011 [PDF]
, 2011 In this paper we examine whether there are systematic differences between the quality of life of an individual who is institutionalised and one who is not, keeping health status and income level constant.
Johansson, Edvard. +2 more
core
Turnover intention of nurses in public hospitals and its association with quality of working life: a cross-sectional survey in six provinces in China. [PDF]
Front Public Health, 2023 Tang C +5 more
europepmc +1 more source