Results 111 to 120 of about 3,829,540 (304)

Relação entre dor crônica e atividade laboral em pacientes portadores de síndromes dolorosas

open access: yesRevista Dor
JUSTIFICATIVA E OBJETIVOS: O presente estudo objetivou identificar a influência da dor crônica no prejuízo da atividade laboral de pacientes atendidos no Serviço de Dor Crônica do Hospital Universitário da Universidade Federal do Maranhão.
Beatriz Tavares Garcia   +2 more
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Improving CE with PDM [PDF]

open access: yes, 2003
The concept of Concurrent Engineering (CE) centers around the management of information so that the right information will be at the right place at the right time and in the right format.
Bondarouk, T.V. (Tanya)   +1 more
core   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Quality of working life of professors in times of social distancing. [PDF]

open access: yesRev Bras Med Trab, 2022
da Silva FX   +3 more
europepmc   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Impact of the COVID-19 crisis on healthcare workers: The need to address quality of working life issues. [PDF]

open access: yesRespirology, 2022
Marcellin F   +7 more
europepmc   +1 more source

QoWL (Quality of Working Life): what, how, and why? [PDF]

open access: yes, 2013
Easton, Simon, Van Laar, Darren
core   +1 more source

Home - About - Disclaimer - Privacy