Results 101 to 110 of about 167,371,403 (279)
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Comparative Analysis of the Quality of Working Life in Ukraine and in EU Countries
Problemy EkorozwojuThe quality of working life is an influential factor in determining the direction of labor movement between countries and between corporations within a country. Countries that offer the best living conditions, financial state support, social integration
Olena Zelenko +2 more
doaj +1 more source
Staff quality of working life and turnover intentions in municipal nursing care and social welfare: a cross-sectional study. [PDF]
BMC Nurs, 2023 Engström M, Jarnheden SH, Tham P.
europepmc +1 more source
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
Quality of working life of professors in times of social distancing. [PDF]
Rev Bras Med Trab, 2022 da Silva FX +3 more
europepmc +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Impact of the COVID-19 crisis on healthcare workers: The need to address quality of working life issues. [PDF]
Respirology, 2022 Marcellin F +7 more
europepmc +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Quality of Work Life (QWL) is a critical factor influencing employee satisfaction, organizational performance, and overallproductivity. This study focuses on analyzing the QWL of employees working in Andhra Pradesh Power GenerationCorporation (APGENCO), a key public sector enterprise responsible for electricity generation in the state.
openaire +2 more sources
Revista Brasileira de EnfermagemEstudo descritivo, correlacional, de corte transversal, cujos objetivos foram avaliar a Qualidade de Vida no Trabalho (QVT) e a presença da Síndrome de Burnout entre profissionais de enfermagem de Unidade de Terapia Intensiva.
Denise Rodrigues Costa Schmidt +4 more
doaj