Results 81 to 90 of about 167,371,403 (279)

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Improving Water Quality in Four Austin Area Streams [PDF]

, 2016
This Working paper provides brief information on a project to improve the water quality of four Austin creeks, including Waller Creek, by reducing the amount of bacteria in the water. The aim of this project is to protect contact recreation in the creeks.
Texas Commission on Environmental Quality
core   +1 more source

Severity of menopausal symptoms on quality of life among working women

Journal of Education and Health Promotion
BACKGROUND: Menopause is experienced by every woman; some women attain it very early as they reach 42 years old. This happens when there is a dysfunction of follicles. The symptoms experienced by the women vary from mild to severe.
S Ramyashree, Jacintha Veigas, Deepa Kanagal   +2 more
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Working Conditions, Work Productivity, Quality of Life, and Depressive Symptoms in Undiagnosed Adults with and without Attention-Deficit/Hyperactivity Disorder (ADHD) Symptoms During the COVID-19 Pandemic

Neuropsychiatric Disease and Treatment, 2022
Toru Nakai,1,* Toshinaga Tsuji,1,* Hiroshi Tsuda,2– 5 Takuma Sotodate,5 Yuki Namba,1 Tatsuhiro Uenishi,6 Katsuhiko Iwasaki,6 Kinya Kokubo,7,8 Hiroaki Tomita9 1Medical Affairs Department, Shionogi & Co., Ltd, Osaka, Japan; 2Clinical Research ...
Nakai T, Tsuji T, Tsuda H, Sotodate T, Namba Y, Uenishi T, Iwasaki K, Kokubo K, Tomita H   +8 more
doaj  

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

A study of relationship Quality of Working Life and its relation with the productivity of nurses in hospitals in Qom: 2016

Journal of Research Development in Nursing and Midwifery, 2019
Background and objectives: Nurses' productivity is a worthy goal of organizations tending to grow. Improving nurse’ QWL is a prerequisite to increase their productivity.
Amirjafar Nazari, Khalil Alimohammadzadeh, Seyed Mojtaba Hosseini   +2 more
doaj   +2 more sources

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas F. Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Health-related quality of life in epilepsy: findings obtained wiht a new italian instrument.

, 2008
The aim of the present study was to evaluate the Epi-QoL, a new Italian-specific measure of health-related quality of life (HRQOL) for adults with epilepsy; the clinical variables that affected the HRQOL score were also assessed.
K. Turner, E. Beghi, M. Ferraroni, LICE Quality Of Life Group, SPECCHIO, LUIGI MARIA, A. Piazzini   +5 more
core   +1 more source