Results 131 to 140 of about 3,829,540 (304)

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Verifying and Validating Quantitative Systems Pharmacology and In Silico Models in Drug Development: Current Needs, Gaps, and Challenges

CPT: Pharmacometrics & Systems Pharmacology, 2020
Flora T. Musuamba, Roberta Bursi, Efthymios Manolis, Kristin Karlsson, Alexander Kulesza, Eulalie Courcelles, Jean‐Pierre Boissel, Raphaëlle Lesage, Cécile Crozatier, Emmanuelle M. Voisin, Cécile F. Rousseau, Thierry Marchal, Rossana Alessandrello, Liesbet Geris   +13 more
doaj   +1 more source

Qualidade de vida no trabalho e burnout em trabalhadores de enfermagem de Unidade de Terapia Intensiva

Revista Brasileira de Enfermagem
Estudo descritivo, correlacional, de corte transversal, cujos objetivos foram avaliar a Qualidade de Vida no Trabalho (QVT) e a presença da Síndrome de Burnout entre profissionais de enfermagem de Unidade de Terapia Intensiva.
Denise Rodrigues Costa Schmidt, Márcia Paladini, Cleonice Biato, Juliana Domingues Pais, Adelaine Rodrigues Oliveira   +4 more
doaj  

Relationships Between Triage Knowledge, Training, Working Experiences and Triage Skills Among Emergency Nurses in East Java, Indonesia [PDF]

, 2013
Background: Since there are increased numbers of clients with traumatic injuries and non-traumatic cases in the emergency department in Indonesia, triage skill is an essential competency required for the emergency nurses.Purposes: This study aimed to ...
Fathoni, M. (Mukhamad), Sangchan, H. (Hathairat), Songwathana, P. (Praneed)   +2 more
core   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Quality of Work Life

Quality of Work Life (QWL) is a critical factor influencing employee satisfaction, organizational performance, and overallproductivity. This study focuses on analyzing the QWL of employees working in Andhra Pradesh Power GenerationCorporation (APGENCO), a key public sector enterprise responsible for electricity generation in the state.
openaire   +2 more sources

Work ability and quality of working life in atopic dermatitis patients treated with dupilumab. [PDF]

J Dermatol, 2021
Bosma AL, Ouwerkerk W, Günal M, Hyseni AM, Arents BWM, Gerbens LAA, Middelkamp-Hup MA, de Boer AGEM, Spuls PI.   +8 more
europepmc   +1 more source

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

FEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas, Porter L. Tomsick, Alicia M. Pickrell, Paul D. Morton   +3 more
wiley   +1 more source

The effect of the work-family conflict, subjective socio-economic status, and physical activity on the perceived quality of life of working women in Iran: the mediating role of quality of work life

BMC Women's Health
Introduction The conflict between work and family responsibilities has created many challenges for working women in Iran. This study aimed to examine the effect of work-family conflict (WFC), subjective socio-economic status (SSS), and physical activity (
Nader Rajabi-Gilan, Shirin Zardoshtian, Neda Sarabi, Mehdi Khezeli   +3 more
doaj   +1 more source

Impaired Quality of Working Life in Inflammatory Bowel Disease Patients. [PDF]

Dig Dis Sci, 2021
van Gennep S, de Boer NKH, Gielen ME, Rietdijk ST, Gecse KB, Ponsioen CY, Duijvestein M, D'Haens GR, Löwenberg M, de Boer AGEM.   +9 more
europepmc   +1 more source