Results 131 to 140 of about 703,438 (302)

Migration Flows and Quality of Life in a Metropolitan Area: the Case of Barcelona-Spain

open access: yes, 2013
The phenomenon of human migration is certainly not new and it has been studied from a variety of perspectives. Yet, the attention on human migration and its determinant has not been fading over time as confirmed by recent contributions (see for instance ...
Faggian, Alessandra   +1 more
core  

Mixed‐class J‐domain protein scaffolds promote expanded aggregate handling and multivalent Hsp70 engagement during functional disaggregase assembly

open access: yesFEBS Letters, EarlyView.
Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley   +1 more source

Evaluating the quality of society and public services

open access: yes, 2010
A person’s quality of life is not only shaped by individual choices and behaviour: the surrounding environment and the public services on offer have a big influence on how people perceive the society they live in and on their evaluation of their own ...
Rose, Richard, Newton, Kenneth
core  

The effect of the work-family conflict, subjective socio-economic status, and physical activity on the perceived quality of life of working women in Iran: the mediating role of quality of work life

open access: yesBMC Women's Health
Introduction The conflict between work and family responsibilities has created many challenges for working women in Iran. This study aimed to examine the effect of work-family conflict (WFC), subjective socio-economic status (SSS), and physical activity (
Nader Rajabi-Gilan   +3 more
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Work ability and quality of working life in atopic dermatitis patients treated with dupilumab. [PDF]

open access: yesJ Dermatol, 2021
Bosma AL   +8 more
europepmc   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

Interurban comparisons of the quality of life [PDF]

open access: yes
A methodology is developed for constructing quality-of-life comparisons for metropolitan areas in which the full bundle of an area's attributes is valued, rather than the typical method of focusing on individual characteristics.Cost and standard of ...
Patricia E. Beeson
core  

Impaired Quality of Working Life in Inflammatory Bowel Disease Patients. [PDF]

open access: yesDig Dis Sci, 2021
van Gennep S   +9 more
europepmc   +1 more source

Home - About - Disclaimer - Privacy