Results 11 to 20 of about 36,076 (121)

Merging Continuous Flow Technology, Photochemistry and Biocatalysis to Streamline Steroid Synthesis

Advanced Synthesis &Catalysis, Volume 365, Issue 23, Page 4024-4048, December 5, 2023., 2023
Abstract Since their structural elucidation in 1935, the introduction and substitution of functional groups and the modification of the steroidal scaffolds have been a fertile ground of research for synthetic and medicinal chemists. The discovery of steroids with hormonal and pharmacological activity has stimulated tremendous efforts to the development
Elena Tomarelli, Bruno Cerra, Francesco G. Mutti, Antimo Gioiello   +3 more
wiley   +1 more source

Transcription factor c‐Rel mediates communication between commensal bacteria and mucosal lymphocytes

Journal of Leukocyte Biology, Volume 111, Issue 5, Page 1001-1007, May 2022., 2022
Graphical Abstract The transcription factor c‐Rel regulates intestinal homeostasis and protects against pathogen colonization; c‐Rel‐deficient mice display defective IgA production in the intestine. Abstract The NF‐κB transcription factor c‐Rel plays a crucial role in promoting and regulating immune responses and inflammation.
Maik Luu, Kai Binder, Sabrina Hartmann, Meike Kespohl, Jasmin Bazant, Rossana Romero, Burkhard Schütz, Ulrich Steinhoff, Alexander Visekruna   +8 more
wiley   +1 more source

Acidic nanoparticles protect against α‐synuclein‐induced neurodegeneration through the restoration of lysosomal function

Aging Cell, Volume 21, Issue 4, April 2022., 2022
We demonstrated that acidic nanoparticles, after intracerebral injection into a α‐synuclein‐based mouse model of PD, attenuated PD‐related neurodegeneration and synucleinopathy by mechanisms involving a rescue of compromised lysosomes. This study demonstrated that strategies enhancing or restoring lysosomal‐mediated degradation thus appear as ...
Marie‐Laure Arotcarena, Federico N. Soria, Anthony Cunha, Evelyne Doudnikoff, Geoffrey Prévot, Jonathan Daniel, Mireille Blanchard‐Desce, Philippe Barthélémy, Erwan Bezard, Sylvie Crauste‐Manciet, Benjamin Dehay   +10 more
wiley   +1 more source

Suivi et quantification de l’urbanisation incontrôlée: une approche basée sur l’analyse multitemporelle des images satellitaires LANDSAT. Cas de la ville de Bou-Saada (Algérie)

Revue Francaise de Photogrammetrie et de Teledetection, 2021
L’urbanisation incontrôlée est actuellement considérée comme l’un des défis majeurs que rencontrent les villes algériennes, compte tenu des effets néfastes sur l’environnement et des problèmes engendrés par cette modalité de croissance spatiale.
Assoule Dechaicha, D. Alkama
semanticscholar   +1 more source

Analysis of pectolytic enzymes and Alternaria spp. in fresh dill, mustard seeds, onions, and vinegar, and their influence on the softening of pickled cucumbers

Journal of Food Science, Volume 87, Issue 2, Page 808-818, February 2022., 2022
Abstract Proteolytic enzymes or fungi have long been identified as causing softening of pickled cucumbers. As the softening of cucumbers occurs mainly in the pasteurized state, this study considers the hypothesis that vinegar and the added spices could be responsible for this softening by studying polygalacturonase (endo‐/exo‐PG), pectinesterase (PE ...
Sabrina Scharf, Anne‐Katrin Kersten, Peter Lentzsch, Peter Meurer   +3 more
wiley   +1 more source

Tree species richness differentially affects the chemical composition of leaves, roots and root exudates in four subtropical tree species

Journal of Ecology, Volume 110, Issue 1, Page 97-116, January 2022., 2022
In the BEF‐China experiment, metabolomics samples were collected from four different species and three organs (a). The metabolomes are species and organ specific (b), and the metabolome specificity is attributed to different chemical classes (c). Tree species diversity affects the metabolome composition (d), but more controlled interaction experiments ...
Alexander Weinhold, Stefanie Döll, Min Liu, Andreas Schedl, Yvonne Pöschl, Xingliang Xu, Steffen Neumann, Nicole M. van Dam   +7 more
wiley   +1 more source

Nodulating white lupins take advantage of the reciprocal interplay between N and P nutritional responses

Physiologia Plantarum, Volume 174, Issue 1, January/February 2022., 2022
Abstract The low bioavailability of nutrients, especially nitrogen (N) and phosphorus (P), is one of the most limiting factors for crop production. In this study, under N‐ and P‐free nutrient solution (−N−P), nodulating white lupin plants developed some nodules and analogous cluster root structures characterized by different morphological ...
Sara Buoso, Anita Zamboni, Alessandro Franco, Mauro Commisso, Flavia Guzzo, Zeno Varanini, Roberto Pinton, Nicola Tomasi, Laura Zanin   +8 more
wiley   +1 more source

Human myocardial mitochondrial oxidative capacity is impaired in mild acute heart transplant rejection

ESC Heart Failure, Volume 8, Issue 6, Page 4674-4684, December 2021., 2021
Abstract Aims Acute cellular rejection (ACR) following heart transplantation (HTX) is associated with long‐term graft loss and increased mortality. Disturbed mitochondrial bioenergetics have been identified as pathophysiological drivers in heart failure, but their role in ACR remains unclear.
Daniel Scheiber, Elric Zweck, Sophie Albermann, Tomas Jelenik, Maximilian Spieker, Florian Bönner, Patrick Horn, Heinz‐Peter Schultheiss, Ganna Aleshcheva, Felicitas Escher, Udo Boeken, Payam Akhyari, Michael Roden, Malte Kelm, Julia Szendroedi, Ralf Westenfeld   +15 more
wiley   +1 more source

Characterization of an Endemic Plant Origanum grosii from Morocco: Trace Element Concentration and Antihyperglycemic Activities

Journal of Chemistry, Volume 2021, Issue 1, 2021., 2021
Origanum genus is one of the most widely used herbs in folk medicine for its biological properties. The present investigation aims to characterize, for the first time, endemic Origanum grosii collected from the Taounate region, Morocco. This characterization was realized by determining the concentration of metals in different parts of the plant ...
H. El hassouni, M. Bouhrim, R. El hajji, M. Bnouham, A. Ziyyat, A. Romane, Murat Senturk   +6 more
wiley   +1 more source

La quantification des données qualitatives : intérêts et difficultés en sciences de gestion

Finance Contrôle Stratégie, 2019
Dans cet article introductif du numero special sur la quantification des donnees qualitatives, nous presentons l’interet et l’ampleur du sujet pour le champ des sciences de gestion.
I. Royer, Lionel Garreau, T. Roulet
semanticscholar   +1 more source