Results 91 to 100 of about 8,273,226 (310)
Desertification is a serious threat to the ecological environment and social economy in our world and there is a pressing need to develop a reasonable and reproducible method to assess it at different scales. In this paper, the Ordos Plateau in China was
Jianjun Pan +4 more
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This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
The principles and models for the quantitative measurement of the financial markets development at macro level (primarily in cases of transitional economies) are reviewed. The assessment is based on expert evaluation of the identified primary indicators,
Algis Žvirblis, Antanas Buračas
doaj +1 more source
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
Expertise for forecasting cotton production in Western Africa: a solution to emerging climate uncertainty?. Description of the subject. Climate uncertainty is expected to have a severe impact on the economy of West African countries.
Ndour, A. +6 more
doaj +1 more source
Quantitative assessment of working conditions in the workplace
Indicators, different in terms of nature and grading scales, are used to recognise hazardous and harmful factors that affect human health. However, no single methodology is available for their assessment, and the variety of qualimetric assessment methods
Cherniak Olena +3 more
doaj +1 more source
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
This article investigates the impact on learning of generic feedback provided automatically after online selected response questions, such as multiple-choice or extended matching questions.
Dermo, John, Carpenter, Liz
core
This report is an addendum to a previous report, "Environmental Assessment of the Expansion of the Mountain View Sewerage Treatment Facilities, Wayne Township, New Jersey," of May 11, 1973.
core +1 more source

