Results 81 to 90 of about 8,273,226 (310)

Discerning protein pools by selective staining with self‐labeling tags

FEBS Letters, EarlyView.
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley   +1 more source

Potentials and pitfalls around green claims of e-fuels: insights from an exploratory case study

Environmental Research Letters
EU and US regulations have recently introduced requirements for calling e-fuels ‘green’ or ‘renewable’, focusing on deliverability and additionality around renewable energy certificates (RECs) in emission inventories.
Caroline H Gebara, Maria Flora Andersen, Edoardo Simioni, Julien Lavalley, Anders Bjørn   +4 more
doaj   +1 more source

Model-free measurement of case influence in structural equation modeling

Frontiers in Psychology
In the field of structural equation modeling (SEM), all commonly used case influence measures are model-based measures whose performance are affected by target-model-misspecification-error.
Fathima Jaffari, Jennifer Koran
doaj   +1 more source

Arctic Monitoring and Assessment Programme Assessment 2013: Arctic Ocean Acidification

, 2013
Report documenting the findings and recommendations of the first comprehensive assessment of Arctic Ocean acidification (AOA) conducted by the Arctic Monitoring and Assessment Programme (AMAP).
Arctic Monitoring and Assessment Programme
core  

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

FEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas, Shahoon Khan, Abhishek Sharma, Byoungchun Lee, Savraj S. Grewal   +4 more
wiley   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Quantifying water erosion’s impact on soil productivity of croplands in China

National Science Open
Soil degradation in croplands caused by water erosion significantly threatens food security. However, quantitative effects of current and future water erosion on soil productivity in croplands remain uncertain.
Yang Xue, Duan Xingwu, Liu Baoyuan, Xie Yun, Siemann Evan, Wang Hongna, Zhang Enwei, Rong Li, Li Yawen, Feng Detai, Lv Huanxu   +10 more
doaj   +1 more source

On Flight Risk Analysis Method Based on Stability Region of Dynamic System Under Icing Conditions

IEEE Access, 2020
The occurrence of loss of control in flight is often accompanied by deep coupling of flight parameters. In order to explore the mechanism of coupling induced flight risk, a method of flight risk assessment based on the stability region of a nonlinear ...
Zhe Li, Xiaocong Duan, Xiaogang Li, Shihao Wang, Yanyan Hou   +4 more
doaj   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Cross-Spatiotemporal Graph Convolution Networks for Skeleton-Based Parkinsonian Gait MDS-UPDRS Score Estimation

IEEE Transactions on Neural Systems and Rehabilitation Engineering
Gait impairment in Parkinson’s Disease (PD) is quantitatively assessed using the Movement Disorder Society Unified Parkinson’s Disease Rating Scale (MDS-UPDRS), a well-established clinical tool. Objective and efficient PD gait assessment is
Haoyu Tian, Haiyun Li, Wenjing Jiang, Xin Ma, Xiang Li, Hanbo Wu, Yibin Li   +6 more
doaj   +1 more source