Results 101 to 110 of about 8,658,301 (256)

Assessment of the state for macrobenthos on solid grounds in the up per sublittoral in certain areas of Avachinsky Bay impacted by harmful algal bloom in autumn 2020, a year after the natural disaster

open access: yesИзвестия ТИНРО
Results of a quantitative diving survey of macrobenthos in the Avachinsky Bay at southeastern Kamchatka in October 2021 are presented. The survey was conducted in a year after the harmful algal bloom (HAB) with mass death of marine organisms in certain ...
Yu. A. Galysheva   +2 more
doaj   +1 more source

Quantitative assessment.

open access: yes, 2019
Total Mean (± standard error) scores on the quantitative assessment for the VR training group (dark grey) and the control group (light grey) at pre-test and post-test.
Tobias Loetscher (324205)   +5 more
core   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

open access: yesMolecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller   +10 more
wiley   +1 more source

Insights into gait performance in Parkinson's disease via latent features of deep graph neural networks

open access: yesFrontiers in Neurology
IntrodcutionParkinson's Disease (PD) is a progressive neurodegenerative disorder that primarily impacts motor function and is prevalent among older adults worldwide.
Jiecheng Wu   +8 more
doaj   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

open access: yesMolecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur   +11 more
wiley   +1 more source

e-Assessment tales: what types of literature are informing day-to-day practice?

open access: yes, 2013
This desktop research commissioned by the Higher Education Academy set out to consult with the academic community about which references on assessment and feedback with technology- enhancement were most useful to practitioners. While all the recommended
Whitelock, Denise   +2 more
core  

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

open access: yesMolecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq   +8 more
wiley   +1 more source

Peer assessment assisted by technology

open access: yes, 2012
A common theme from the National Student Survey is that students want more feedback, but increasing the amount of teacher-student feedback is not practicable. Peer assessment, if carefully supported, can be a cost-effective solution.
Barr, Niall   +7 more
core  

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

open access: yesMolecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park   +6 more
wiley   +1 more source

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

open access: yesMolecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach   +9 more
wiley   +1 more source

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