Results 41 to 50 of about 336,593 (263)

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Sensory profile and contribution of major components of aroma in dry red wine quality

Vértices, 2012
This study aimed to determine the sensory profile and main volatile compounds of a set of commercial wines from two major wine regions in Brazil. A total of 28 descriptors were selected by quantitative descriptive analysis, and “red”, “violet”, “pungent ...
Luisa Costa de Oliveira, Maria Eugênia de Oliveira Mamede   +1 more
doaj   +1 more source

Descriptive Sensory Profile and Consumer Study Impact of Different Nutritive and Non-Nutritive Sweeteners on the Descriptive, Temporal Profile, and Consumer Acceptance in a Peach Juice Matrix

Foods, 2022
The study evaluated the effect of peach juice sweetened with sucrose, widely used non-nutritive sweeteners, the artificial sucralose, neotame blend, and the natural stevia extract with different rebaudioside A concentrations on the temporal and ...
Alessandra Medeiros, Elson Tavares, Helena Maria Andre Bolini   +2 more
doaj   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

FEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai, Mohyeddine Omrane, Nassima Benzoubir, Didier Samuel, Ama Gassama‐Diagne   +4 more
wiley   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Sensory characteristics and biochemical basis of small-leaf group varieties of Chinese Sichuan black tea

Scientific Reports
This study combined Quantitative Descriptive Analysis (QDA), PanelCheck, partial least squares regression (PLSR), partial least squares discriminant analysis (PLS-DA), and hierarchical cluster analysis to investigate the sensory quality of Sichuan small ...
Tingting Feng, Xiang Li, Xun Fu, Wenling Zhang, Chunmei Xiong, Yan Zhang   +5 more
doaj   +1 more source

Challenges and a response strategy for the development of nursing in China: a descriptive and quantitative analysis [PDF]

Journal of Evidence-Based Medicine, 2013
AbstractObjectiveTo assess the challenges to and provide a response strategy for the development of nursing and make suggestions for promoting the nursing discipline, platform, and talent teams based on current best available evidence.MethodsWe searched CNKI(China National Knowledge Infrastructure), VIP information(Chinese Scientific Journals database),
Yingqiang, Wang, Shiyou, Wei, Youping, Li, Shaolin, Deng, Qianqian, Luo, Yan, Li   +5 more
openaire   +2 more sources

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

FEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Quantitative Structural Description of Zeolites by Machine Learning Analysis of Infrared Spectra

Inorganic Chemistry, 2023
Application of machine learning (ML) algorithms to spectroscopic data has a great potential for obtaining hidden correlations between structural information and spectral features. Here, we apply ML algorithms to theoretically simulated infrared (IR) spectra to establish the structure-spectrum correlations in zeolites. Two hundred thirty different types
Alina A. Skorynina, Bogdan O. Protsenko, Oleg A. Usoltsev, Sergey A. Guda, Aram L. Bugaev   +4 more
openaire   +2 more sources