Results 61 to 70 of about 31,502 (199)
Evaluation of Core Competencies in Compulsory Music Education: A Delphi-based Study on Empowerment
Jiaoshi jiaoyu xuebaoEducational evaluation is essential for the development of education, and shifting from knowledge evaluation to core competency evaluation is a crucial step in today's educational evaluation reform.
WEN Ling, DING Pan
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Haiyang Kaifa yu guanli, 2022 Taking Guangxi Beibu Gulf mariculture area as an example, the fuzzy mathematics grey statistics and entropy weight TOPSIS method were used to establish the ecological environment pressure evaluation system of Guangxi Beibu Gulf mariculture, and the Arc ...
Shenglong CHENG +4 more
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Lingual frenulum: Quantitative evaluation proposal
International Journal of Orofacial Myology, 2005 The purpose of this study was to establish a quantitative method to classify lingual frenulum as normal and altered. Methods: 98 people were included in this study. All measurements were made with maxium opening of the mouth. A digital caliper was used to measure the length of the frenulum under three conditions: a) with the tongue tip on the ...
openaire +3 more sources
Molecular Oncology, EarlyView.The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola +12 more
wiley +1 more source
ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
Molecular Oncology, EarlyView.We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source
Biomechanical mechanism and clinical management progress of surgical wound tension
Frontiers in SurgerySurgical wound tension, a core biomechanical factor in tissue repair, is clinically important because high tension can cause microcirculatory disturbances, leading to inhibition of cell migration and collagen deposition, and increasing complications such
Feiyu Gong +6 more
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Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
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Research on quantitative evaluation method of flight technology combining artificial and data
Hangkong gongcheng jinzhanThe evaluation of flight technology runs through the whole flight process，and the objective and fair evaluation is of great significance to the improvement of pilot technology，which is of great significance to the flight safety of China's civil aviation.
LIU Wei, LIU Yuyan, YANG Yong
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