Results 21 to 30 of about 391,632 (299)

QTLMAS 2009: simulated dataset [PDF]

open access: yes, 2010
Background - The simulation of the data for the QTLMAS 2009 Workshop is described. Objective was to simulate observations from a growth curve which was influenced by a number of QTL.
Coster, A.   +12 more
core   +1 more source

Prioritizing candidate genes post-GWAS using multiple sources of data for mastitis resistance in dairy cattle

open access: yesBMC Genomics, 2018
Background Improving resistance to mastitis, one of the costliest diseases in dairy production, has become an important objective in dairy cattle breeding. However, mastitis resistance is influenced by many genes involved in multiple processes, including
Zexi Cai   +3 more
doaj   +1 more source

Genetical genomics: spotlight on QTL hotspots [PDF]

open access: yes, 2008
No abstract ...
Andrew I Su   +49 more
core   +1 more source

Dissecting closely linked association signals in combination with the mammalian phenotype database can identify candidate genes in dairy cattle

open access: yesBMC Genetics, 2019
Background Genome-wide association studies (GWAS) have been successfully implemented in cattle research and breeding. However, moving from the associations to identify the causal variants and reveal underlying mechanisms have proven complicated. In dairy
Zexi Cai   +3 more
doaj   +1 more source

Prioritizing candidate genes for fertility in dairy cows using gene-based analysis, functional annotation and differential gene expression

open access: yesBMC Genomics, 2019
Background An unfavorable genetic correlation between milk production and fertility makes simultaneous improvement of milk production and fertility difficult in cattle breeding. Rapid genetic improvement in milk production traits in dairy cattle has been
Zexi Cai   +3 more
doaj   +1 more source

Mapping quantitative trait loci and identification of genes that control fatness in poultry

open access: yes, 2002
Chicken genomics has benefited from the rapid technological advances in the genomics of model organisms and man. A number of resources and approaches are now well established, in the chicken, including genetic markers and maps (both genetic and physical),
Hocking, Paul M   +3 more
core   +1 more source

Selection responses of means and inbreeding depression for female fecundity in Drosophila melanogaster suggest contributions from intermediate-frequency alleles to quantitative trait variation [PDF]

open access: yes, 2007
The extent to which quantitative trait variability is caused by rare alleles maintained by mutation, versus intermediate-frequency alleles maintained by balancing selection, is an unsolved problem of evolutionary genetics.
Borthwick, Helen   +2 more
core   +1 more source

Weighting sequence variants based on their annotation increases the power of genome-wide association studies in dairy cattle

open access: yesGenetics Selection Evolution, 2019
Background Genome-wide association studies (GWAS) are widely used to identify regions of the genome that harbor genetic determinants of quantitative traits.
Zexi Cai   +3 more
doaj   +1 more source

Estimation of variance components and prediction of breeding values based on group records from varying group sizes

open access: yesGenetics Selection Evolution, 2018
Background Records on groups of individuals rather than on single individuals could be valuable for predicting breeding values (BV) of the traits that are difficult or costly to measure individually, such as feed intake in pigs or beef cattle.
Guosheng Su   +6 more
doaj   +1 more source

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