Results 41 to 50 of about 391,632 (299)

Impact of rare and low-frequency sequence variants on reliability of genomic prediction in dairy cattle

Genetics Selection Evolution, 2018
Background Availability of whole-genome sequence data for a large number of cattle and efficient imputation methodologies open a new opportunity to include rare and low-frequency variants (RLFV) in genomic prediction in dairy cattle.
Qianqian Zhang, Goutam Sahana, Guosheng Su, Bernt Guldbrandtsen, Mogens Sandø Lund, Mario P. L. Calus   +5 more
doaj   +1 more source

Strategies Using Genomic Selection to Increase Genetic Gain in Breeding Programs for Wheat

Frontiers in Genetics, 2020
Conventional wheat-breeding programs involve crossing parental lines and subsequent selfing of the offspring for several generations to obtain inbred lines. Such a breeding program takes more than 8 years to develop a variety.
Biructawit Bekele Tessema, Huiming Liu, Anders Christian Sørensen, Jeppe Reitan Andersen, Just Jensen   +4 more
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

SNP markers associated with body size and pelt length in American mink (Neovison vison)

BMC Genetics, 2018
Background Identification of genes underlying production traits is a key aim of the mink research community. Recent availability of genomic tools have opened the possibility for faster genetic progress in mink breeding.
Zexi Cai, Trine Michelle Villumsen, Torben Asp, Bernt Guldbrandtsen, Goutam Sahana, Mogens Sandø Lund   +5 more
doaj   +1 more source

Assessing Population Structure and Signatures of Selection in Wanbei Pigs Using Whole Genome Resequencing Data

Animals, 2022
Wanbei pig (WBP) is one of the indigenous pig resources in China and has many germplasm characteristics. However, research on its genome is lacking. To assess the genomic variation, population structure, and selection signatures, we resequenced 18 WBP ...
Wei Zhang, Linqing Liu, Mei Zhou, Shiguang Su, Lin Dong, Xinxin Meng, Xueting Li, Chonglong Wang   +7 more
doaj   +1 more source

Genetic variation and quantitative trait loci associated with developmental stability and the environmental correlation between traits in maize

, 2008
There is limited experimental information about the genetic basis of micro-environmental variance (V-E) (developmental stability) and environmental correlations.
Hill, William G., Malvar Pintos, Rosa Ana, Ordas, Bernardo, Ordás López, Bernardo, Malvar, Rosa A.   +4 more
core   +1 more source

A multivariate analysis of genetic constraints to life history evolution in a wild population of red deer [PDF]

, 2014
The long-term study has been largely funded by the Natural Environment Research Council (NERC). This research was supported by a NERC grant (to L.E.B.K., T.H.C.-B., and J.M.P.), a NERC postdoctoral fellowship (to C.A.W.), a National Sciences and ...
Walling, Craig, Pemberton, Josephine M, Kruuk, Loeske, Morrissey, Michael Blair, Clutton-Brock, Tim H, Foerster, Katharina, Clutton-Brock, Tim, Morrissey, Michael B., Kruuk, Loeske E B, Clutton-Brock, Tim H., Pemberton, Josephine M., Walling, Craig A., Pemberton, Josephine   +12 more
core   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

The effect of phenotyping, adult selection, and mating strategies on genetic gain and rate of inbreeding in black soldier fly breeding programs

Genetics Selection Evolution
Background The aim of this study was to compare genetic gain and rate of inbreeding for different mass selection breeding programs with the aim of increasing larval body weight (LBW) in black soldier flies. The breeding programs differed in: (1) sampling
Margot Slagboom, Hanne Marie Nielsen, Morten Kargo, Mark Henryon, Laura Skrubbeltrang Hansen   +4 more
doaj   +1 more source