Results 181 to 190 of about 6,396,260 (376)

Aberrant expression of nuclear prothymosin α contributes to epithelial‐mesenchymal transition in lung cancer

open access: yesMolecular Oncology, EarlyView.
Nuclear prothymosin α inhibits epithelial‐mesenchymal transition (EMT) in lung cancer by increasing Smad7 acetylation and competing with Smad2 for binding to SNAI1, TWIST1, and ZEB1 promoters. In early‐stage cancer, ProT suppresses TGF‐β‐induced EMT, while its loss in the nucleus in late‐stage cancer leads to enhanced EMT and poor prognosis.
Liyun Chen   +12 more
wiley   +1 more source

Evaluation of blood-brain barrier integrity by the analysis of dynamic contrast-enhanced MRI - a comparison of quantitative and semi-quantitative methods. [PDF]

open access: yesPhysiol Res, 2022
Kala D   +9 more
europepmc   +1 more source

Using Quantitative Methods as Support for Audit of the Distributed Informatics Systems [PDF]

open access: yes
This paper highlights some issues regarding how an indicators system must be developed and used in an audit process. Distributed systems are presented from de points of view of their main properties, architectures, applications, software quality ...
Marius POPA, Sergiu Marin CAPISIZU
core  

Determination of ADP/ATP translocase isoform ratios in malignancy and cellular senescence

open access: yesMolecular Oncology, EarlyView.
The individual functions of three isoforms exchanging ADP and ATP (ADP/ATP translocases; ANTs) on the mitochondrial membrane remain unclear. We developed a method for quantitatively differentiating highly similar human ANT1, ANT2, and ANT3 using parallel reaction monitoring. This method allowed us to assess changes in translocase levels during cellular
Zuzana Liblova   +18 more
wiley   +1 more source

The pathways of unaccompanied foreign minors evaluated by the social workers: a case study in Italy

open access: yesGenus
Social workers, who are responsible for unaccompanied minors (UAM), have in-depth knowledge of those minors’ backgrounds and the reception pathways they follow. The social workers support key aspects of UAM integration such as learning the host country’s
Laura Terzera, Paolo Bonomi
doaj   +1 more source

Early metastasis is characterized by Gr1+ cell dysregulation and is inhibited by immunomodulatory nanoparticles

open access: yesMolecular Oncology, EarlyView.
Breast cancer metastasis is associated with myeloid cell dysregulation and the lung‐specific accumulation of tumor‐supportive Gr1+ cells. Gr1+ cells support metastasis, in part, through a CHI3L1‐mediated mechanism, which can be targeted and inhibited with cargo‐free, polymeric nanoparticles.
Jeffrey A. Ma   +9 more
wiley   +1 more source

Quantitative Methods to Detect Suicide and Self-Harm Clusters: A Systematic Review. [PDF]

open access: yesInt J Environ Res Public Health, 2022
Benson R   +5 more
europepmc   +1 more source

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