Results 41 to 50 of about 6,348,682 (283)

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Common Biases In Business Research [PDF]

open access: yes, 2018
In research, bias occurs when an error is introduced into sampling or testing which results in selecting or encouraging one outcome, conclusion, or answer over others.
A Oppenheim   +6 more
core   +1 more source

Exploring the Influence of Crime on NEET Rates: A Regional Analysis of Italy

open access: yesMerits
The occurrence of criminal activities has the potential to hinder socioeconomic advancement, preventing individuals from investing in human capital and pursuing employment opportunities.
Iacopo Odoardi   +3 more
doaj   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

open access: yesFEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Methods for a quantitative evaluation of odd-even staggering effects

open access: yes, 2015
Odd-even effects, also known as "staggering" effects, are a common feature observed in the yield distributions of fragments produced in different types of nuclear reactions. We review old methods, and we propose new ones, for a quantitative estimation of
Olmi, Alessandro, Piantelli, Silvia
core   +1 more source

Integrating case study and survey research methods: An example in information systems [PDF]

open access: yes, 1994
The case for combining research methods generally, and more specifically that for combining qualitative and quantitative methods, is strong. Yet, research designs that extensively integrate both fieldwork (e.g. case studies) and survey research are rare.
Gable, Guy G.
core   +3 more sources

Time after time – circadian clocks through the lens of oscillator theory

open access: yesFEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo   +2 more
wiley   +1 more source

A researcher's dilemma- philosphical and methodological pluralism [PDF]

open access: yes, 2004
In many research textbooks the distinction between qualitative and quantitative research is inadvertently linked with philosophical perspectives. This in essence creates a mutually exclusive relationship between method and philosophy.
Knox, KT
core  

Improving statistical inference on pathogen densities estimated by quantitative molecular methods: malaria gametocytaemia as a case study [PDF]

open access: yes, 2015
BACKGROUND: Quantitative molecular methods (QMMs) such as quantitative real-time polymerase chain reaction (q-PCR), reverse-transcriptase PCR (qRT-PCR) and quantitative nucleic acid sequence-based amplification (QT-NASBA) are increasingly used to ...
A Gelman   +56 more
core   +4 more sources

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