Results 61 to 70 of about 12,300,510 (297)

20220228_RAG_Risk assessment pandemic law_FR

, 2022
RAG RA pandemic  ...
Risk Assessment Group
core  

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Contract farming risks: A quantitative assessment

South African Journal of Economic and Management Sciences, 2016
The objective of this study is to identify the key risks facing each of the stakeholders in the export-focused paprika value chain in Zambia. Although a deterministic cost-benefit analysis indicated that this outgrower scheme would have a very satisfactory net present value (NPV), a Monte Carlo analysis using an integrated financial–economic ...
Kabungo, Arkins M., Jenkins, Glenn P.
openaire   +6 more sources

20220228_RAG_Risk assessment pandemic law_NL

, 2022
RAG RA pandemic  ...
Risk Assessment Group
core  

Probabilistic cumulative risk assessment of anti-androgenic pesticides in food [PDF]

, 2008
In this paper, we present a cumulative risk assessment of three anti-androgenic pesticides (vinclozolin, procymidone and prochloraz) using the relative potency factor (RPF) approach and an integrated probabilistic risk assessment (IPRA) model.
Nielsen, E., Dep IRAS, Ladefoged, O., Bosgra, S., Voet, H. van der, Risk Assessment of Toxic and Immunomodulatory Agents, Boon, P. E., Boon, P.E., Müller, Anne Kirstine, Boon, Polly E., van der Voet, Hilko, Bosgra, Sieto, Voet, H., van der, Ladefoged, Ole, Nielsen, Elsa, van der Voet, H., Müller, A.K.   +16 more
core   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

20220110_RAG_Risk assessment pandemic law_FR

, 2022
RAG RA pandemic  ...
Risk Assessment Group
core  

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Quantitative Risk Assessment to Site Cng Refuelling Stations

Chemical Engineering Transactions, 2010
preview not available - see full-text PDF article.
N. Badri, F. Nouraei, D. Rashtchian
doaj   +1 more source

On long-term credit risk assessment and rating : Towards a new set of models [PDF]

, 2009
Technical ReportInstitutional investors are supposed to assess credit risk by using a combination of quantitative information such as option models and qualitative assessments.
Kubo, Hideya, Sakai, Yasuhiro
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