Results 61 to 70 of about 681,680 (256)
Molecular Oncology, EarlyView.Circulating tumor cells (CTCs) and plasma cell‐free DNA (cfDNA) were analyzed to detect ESR1 mutations and methylation in patients with advanced breast cancer. CTC‐derived DNA showed higher sensitivity for mutation detection and revealed complementary genetic and epigenetic alterations, highlighting the added value of CTC analysis for understanding ...
Dimitra Stergiopoulou +12 more
wiley +1 more source
ENDÜSTRİYEL TESİSLERDE RİSK ANALİZİNE YÖNELİK KULLANILAN VERİ KAYNAKLARI VE BİR UYGULAMA
Eskişehir Osmangazi Üniversitesi Mühendislik ve Mimarlık Fakültesi Dergisi, 2020 Today's rapidly changing living conditions and increasing consumer needs lead to continuous differentiation of working conditions. This situation builds extra stress on workers which leads to possible new risks and dangers where it ...
Neslihan BABAARSLAN, Yavuz CABBAR
doaj +1 more source
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
New Microbes and New InfectionsBackground: Legionella pneumophila poses a significant health risk in hospital water systems. This study assessed the risk associated with Legionella contamination in a hospital drinking water system in Sari, Iran, over one year.
Seyed Mohammad Ranjdoost, Mina Owrang
doaj +1 more source
Quantitative Risk Assessment to Site Cng Refuelling Stations
Chemical Engineering Transactions, 2010 preview not available - see full-text PDF article.
N. Badri, F. Nouraei, D. Rashtchian
doaj +1 more source
Molecular Oncology, EarlyView.A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel +12 more
wiley +1 more source
Q4MRATools: Quantitative tools to microbial risk assessment
EFSA JournalIn the context of the European Food Risk Assessment (EU‐FORA) fellowship programme, the project ‘Q4MRATools: Quantitative Tools to Microbial Risk Assessment’ focused on training in predictive microbiology, experimental design and the use of advanced ...
Olga María Bonilla Luque +5 more
doaj +1 more source
Quantitative Risk Assessment on a Hydrogen Refuelling Station
Chemical Engineering Transactions, 2018 The Directive 2014/94/UE (DAFI, Alternative Fuel Initiative Directive) on the deployment of alternative fuels (i.e. hydrogen) infrastructures has been recently transposed into national law in Italy.
Paola Russo +3 more
doaj +1 more source
Quantitative Risk Assessment of Environmental Hazards [PDF]
Annual Review of Public Health, 1985 Quantitative risk assessment may never become a rigorous scientific discipline because of the inherent difficulties in working with highly uncertain and often controversial data and methods, and because the predictions of risk assessment may not be subject to validation in their most important areas of application.
openaire +2 more sources
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source