Quantitative Risk Assessment of Environmental Hazards [PDF]
Quantitative risk assessment may never become a rigorous scientific discipline because of the inherent difficulties in working with highly uncertain and often controversial data and methods, and because the predictions of risk assessment may not be subject to validation in their most important areas of application.
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Semi-quantitative risk assessment of marine mammal oil exposure: A case study in the western Gulf of Mexico [PDF]
M. Rafael Ramírez‐León +7 more
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NKCC1: A key regulator of glioblastoma progression
Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen +5 more
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Yuncong Wang, Lihong Wang, Xia Zhao, Jingli Zhang, Wenhui Ma, Huijie Zhao, Xu Han Hospital Infection Management Division, Xuan Wu Hospital Capital Medical University, Beijing, People’s Republic of ChinaCorrespondence: Lihong WangDirector of ...
Wang Y +6 more
doaj
Quantitative BSE risk assessment: relating exposures to risk [PDF]
There is currently no epidemiological evidence to identify the route(s) of transmission of BSE from cattle to humans, although consumption of infected bovine offals, prior to their use being banned in human food in late 1989, is the most likely source.
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Overview of molecular signatures of senescence and associated resources: pros and cons
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas +6 more
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RiskTree: Decision trees for asset and process risk assessment quantification in big data platforms
Currently, big data platforms are widely applied across various industries. These platforms are characterized by large scale, diverse forms, high update frequency, and rapid data flow, making it challenging to directly apply existing risk quantification ...
Zhan Haomou +7 more
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Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity
Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz +9 more
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Carcinogen Risk Assessment: New Directions in the Qualitative and Quantitative Aspects. Banbury Report 31. Edited by Ronald W. Hart and Fred D. Hoerger. New York: Cold Spring Harbor Laboratory. 1988. 308 pages. Cloth $85.00 ISBN 0 87969 231 6. [PDF]
James M. Parry
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We established a spheroid coculture system enabling viable Porphyromonas gingivalis–HNSCC interactions under normoxic conditions. Inhibition of LATS1/2 maintains tumor cells in an undifferentiated state, which may promote spheroid growth and create a more permissive environment for bacterial persistence.
Yurika Nakajima +4 more
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