Results 241 to 250 of about 19,356,818 (281)

STERIC EFFECTS IN QUANTITATIVE STRUCTURE-ACTIVITY RELATIONSHIPS

Pure and Applied Chemistry, 1978
Abstract
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Quantitative structure - activity relationships of cardiotonic agents

2000
Quantitative structure-activity relationships (QSARs) of different cardiotonic agents are presented. A critical analysis of all QSARs provides a very vivid picture of the mechanisms of varying cardiotonic agents. The cardiotonics can be broadly put into 2 categories: cardiac glycosides and nonglycoside cardiotonics, which include phosphodiesterase of ...
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Quantitative structure-activity relationships of antianginal drugs

2001
Quantitative structure-activity relationships (QSARs) of various classes of antianginal drugs, e.g. nitrates, beta-adrenergic blocking agents (beta-blockers), and calcium channel blockers (calcium antagonists), have been reviewed. This review gives an overall picture of the mode of action of each class of drugs and points out the specific ...
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Quantitative structure-activity relationships for skin permeability

Toxicology in Vitro, 1995
In vitro human skin permeability coefficient data collected by Flynn (1990) have been analysed using multiple regression analysis. An improved model for the prediction of permeability coefficients has been derived by the inclusion of the melting point as an independent variable in addition to the octanol-water partition coefficient (as logP) and ...
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Chromatography in studies of quantitative structure-activity relationships

Journal of Chromatography A, 1981
The rational bases, experimental techniques and conditions required for the chromatographic determination of the structural data of importance for studies on quantitative relationships between chemical structure and biological activity of drugs (QSAR) are reviewed. Practical applications of the information gathered from various chromatographic modes in
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Quantitative Structure-Activity Relationship (QSAR)

Quantitative Structure–Activity Relationship (QSAR), also known as Hubungan Kuantitatif Struktur dan Aktivitas (HKSA), is a pivotal computational strategy in the design of novel compounds. This review provides a comprehensive overview of the QSAR/HKSA framework, encompassing theoretical concepts, descriptor generation, physicochemical property ...
Sani, Ihya Zakira, Ananta Nazira Meliano, Zainul, Rahadian, Indah Handini Putri, Afif, Iffat Syafiqoh, Putri, Tabitha Oschika, Atika suri   +6 more
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Quantitative structure-activity relationships of antihypertensive agents

1999
Quantitative structure-activity relationships of various classes of antihypertensive agents, e.g., sympatholytic agents, diuretics, direct or peripheral vasodilators, potassium channel activators, angiotensin-converting enzyme inhibitors, renin inhibitors and miscellaneous agents (platelet aggregation inhibitors) are reviewed.
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QUANTITATIVE APPROACHES TO STRUCTURE–ACTIVITY RELATIONSHIPS

2003
Han van de Waterbeemd, Sally Rose
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Quantitative Structure-Activity Relationship and Cytotoxicity

2015
N K, Mize, J A, Johnson, C, Hansch, M, Cormier   +3 more
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Quantitative structure-activity relationships

Toxicology in Vitro, 1989
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