Results 51 to 60 of about 1,790,645 (373)

Quantitative Structure Activity Relationship of Cinnamaldehyde Compounds against Wood-Decaying Fungi

open access: yesMolecules, 2016
Cinnamaldehyde, of the genius Cinnamomum, is a major constituent of the bark of the cinnamon tree and possesses broad-spectrum antimicrobial activity.
Dongmei Yang   +3 more
doaj   +1 more source

Structure-activity relationships based on 3D-QSAR CoMFA/CoMSIA and design of aryloxypropanol-amine agonists with selectivity for the human β3-adrenergic receptor and anti-obesity and anti-diabetic profiles [PDF]

open access: yes, 2018
Indexación: Scopus.Acknowledgments: This work was supported by FONDECYT No. 11130701. We would also like to thank fDoTr CthLeafbr efeora vthaeil afrbeilei tayvoafiltahbeilsitoyf towfa trheer seoqfutwireadret orecqaulciureladt etothcealAcuDla(thet ttph:e/
Andrades-Lagos, J.   +7 more
core   +2 more sources

Quantitative structure‐activity relationship and molecular docking revealed a potency of anti‐hepatitis C virus drugs against human corona viruses

open access: yesJournal of Medical Virology, 2017
A number of human coronaviruses (HCoVs) were reported in the last and present centuries. Some outbreaks of which (eg, SARS and MERS CoVs) caused the mortality of hundreds of people worldwide. The problem of finding a potent drug against HCoV strains lies
Abdo A. Elfiky   +2 more
semanticscholar   +1 more source

QSAR studies on Withanolide analogs for anticancer activity [PDF]

open access: yes, 2011
Withanolides are a group of pharmacologically active compounds present in most prodigal amounts in roots and leaves of Withania somnifera (Indian ginseng), one of the most important medicinal plants of Indian systems of medicine.
Dharmendra Kumar Yadav   +2 more
core   +2 more sources

Quantitative structure-activity relationship to elucidate human CYP2A6 inhibition by organosulfur compounds

open access: yesADMET and DMPK, 2019
CYP2A6 is a human enzyme responsible for the metabolic elimination of nicotine, and it is also involved in the activation of procarcinogenic nitrosamines, especially those present in tobacco smoke.
Daniela Andrea Ramirez   +3 more
doaj   +1 more source

Toward Novel Antioxidant Drugs: Quantitative Structure-Activity Relationship Study of Eugenol Derivatives

open access: yesWalisongo Journal of Chemistry, 2021
The study of the Quantitative Structure-Activity Relationship (QSAR) of eugenol compound and its derivatives towards antioxidant activities was conducted using electronic and molecular descriptors.
Priyagung Dhemi Widiakongko   +1 more
doaj   +1 more source

Quantitative structure-activity relationship for antimalarial activity of artemisinin [PDF]

open access: yes, 2010
The increase in resistance to older drugs and the emergence of new types of infection have created an urgent need for discovery and development of new compounds with antimalarial activity.
Hasan, Mohamed Noor   +1 more
core  

The effect of lipophilicity on the antibacterial activity of some 1-benzylbenzimidazole derivatives [PDF]

open access: yes, 2008
In the present paper, the antibacterial activity of some 1-benzylbenzimidazole derivatives were evaluated against the Gram-negative bacteria Escherichia coli. The minimum inhibitory concentration was determined for all the compounds.
D. D. CVETKOVIC   +2 more
core   +1 more source

B cell mechanobiology in health and disease: emerging techniques and insights into therapeutic responses

open access: yesFEBS Letters, EarlyView.
B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro   +2 more
wiley   +1 more source

Assessing the Effects of Alloxydim Phototransformation Products by QSAR Models and a Phytotoxicity Study

open access: yesMolecules, 2018
Once applied, an herbicide first makes contact with leaves and soil. It is known that photolysis can be one of the most important processes of dissipation of herbicides in the field.
Juan J. Villaverde   +4 more
doaj   +1 more source

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