Quantitative Structure Activity Relationship Studies of Topoisomerase I Inhibitors as Potent Antibreast Cancer Agents [PDF]
, 2013 Topoisomerase I (TOP I) is a valuable molecular target for the development of clinically used anticancer agents. Indenoisoquinolines have emerged as potent topoisomerase I inhibitors.
Anubhuti Pandey +4 more
core +1 more source
DESIGN OF HYDROXY XANTHONES DERIVATIVES AS ANTICANCER USING QUANTITATIVE STRUCTURE-ACTIVITY RELATIONSHIP [PDF]
, 2016 Objective: The objective of the research is to design a new hydroxy xanthone derivative has anticancer activity using quantitative structure-activityrelationship (QSAR).Methods: The QSAR designed new compounds were calculated by parameterized model 3 ...
Jumina, Jumina +3 more
core +1 more source
Quantitative notions of rectifiability in the Heisenberg groups [PDF]
arXiv, 2019 Several quantitative notions of rectifiability in the Heisenberg groups have emerged in the recent literature. In this paper we study the relationship between two of them, the big pieces of intrinsic Lipschitz graphs (BPiLG) condition and the bilateral weak geometric lemma (BWGL), and show that sets with BPiLG satisfy the BWGL.
arxiv
Quantum Chemical QSAR Models to Distinguish Between Inhibitory Activities of Sulfonamides Against Human Carbonic Anhydrases I and II and Bovine IV Isozymes [PDF]
, 2012 Linear and nonlinear quantitative structure activity relationship models for predicting the inhibitory activities of sulfonamides toward different carbonic anhydrase isozymes were developed based on multilinear regression, principal component-artificial ...
Deeb, Omar +2 more
core
INSILICO EVALUATION OF ANTISMOKING ACTIVITY OF ERYTHRININE: A COMPUTATIONAL COMPARISON AGAINST CYTISINE [PDF]
, 2016 Objectives: Erythrinine is a new ring-C-oxygenated Erythrina alkaloid from plant sources Erythrina Indica. The aim of this study is to investigate the smoking cessation activity of Erythrinine and its analogues using in silico computational approach ...
Muthukumar, Vijeyaanandhi +1 more
core +1 more source
On the Augmented Zagreb Index [PDF]
Kuwait J. Sci. 43(2), (2016) 48-63, 2014 Topological indices play an important role in mathematical chemistry especially in the quantitative structure-property relationship (QSPR) and quantitative structure-activity relationship (QSAR). Recent research indicates that the augmented Zagreb index (AZI) possess the best correlating ability among several topological indices.
arxiv
SDE in Random Population Growth [PDF]
arXiv, 2008 In this paper we extend the recent work of C.A. Braumann \cite{B2007} to the case of stochastic differential equation with random coefficients. Furthermore, the relationship of the It\^o-Stratonovich stochastic calculus to studies of random population growth is also explained.
arxiv
Information-theoretic Interestingness Measures for Cross-Ontology Data Mining [PDF]
arXiv, 2015 Community annotation of biological entities with concepts from multiple bio-ontologies has created large and growing repositories of ontology-based annotation data with embedded implicit relationships among orthogonal ontologies. Development of efficient data mining methods and metrics to mine and assess the quality of the mined relationships has not ...
arxiv
Quantitative Structure-Activity Relationship in the Series of 5-Ethyluridine, N2-Guanine, and 6-Oxopurine Derivatives with Pronounced Anti-Herpetic Activity. [PDF]
Molecules, 2023 Khairullina V, Martynova Y.
europepmc +1 more source
Dataset on aquatic ecotoxicity predictions of 2697 chemicals, using three quantitative structure-activity relationship platforms. [PDF]
Data Brief, 2023 Svedberg P +5 more
europepmc +1 more source