Iron deposition in Parkinson’s disease by quantitative susceptibility mapping [PDF]
Background Patients with Parkinson’s disease (PD) have elevated levels of brain iron, especially in the nigrostriatal dopaminergic system. The purpose of this study was to evaluate the iron deposition in the substantia nigra (SN) and other deep gray ...
Qiqi Chen+7 more
doaj +5 more sources
Quantitative Susceptibility Mapping in Parkinson's Disease.
BackgroundQuantitative susceptibility mapping (QSM) and R2* relaxation rate mapping have demonstrated increased iron deposition in the substantia nigra of patients with idiopathic Parkinson's disease (PD).
Christian Langkammer+16 more
doaj +3 more sources
Temporal Shift When Comparing Contrast-Agent Concentration Curves Estimated Using Quantitative Susceptibility Mapping (QSM) and ΔR2*: The Association Between Vortex Parameters and Oxygen Extraction Fraction [PDF]
Background: When plotting data points corresponding to the contrast-agent-induced change in transverse relaxation rate from a dynamic gradient-echo (GRE) magnetic resonance imaging (MRI) study versus a corresponding spin-echo study, a loop or vortex ...
Ronnie Wirestam+3 more
doaj +2 more sources
Correlation between iron deposition and cognitive function in mild to moderate Alzheimer’s disease based on quantitative susceptibility mapping [PDF]
BackgroundAlzheimer’s disease (AD) is a complex neurodegenerative disorder characterized by progressively worsening cognitive decline and memory loss. Excessive iron accumulation produces severe cognitive impairment.
Yuqi Zhi+9 more
doaj +2 more sources
Characterization of quantitative susceptibility mapping in the left ventricular myocardium [PDF]
: Background: Myocardial quantitative susceptibility mapping (QSM) may offer better specificity to iron than conventional T2* imaging in the assessment of cardiac diseases, including intra-myocardial hemorrhage.
Andrew Tyler+7 more
doaj +2 more sources
Editorial: Quantitative susceptibility mapping: technical advances and clinical applications [PDF]
Hongjiang Wei+3 more
doaj +2 more sources
PurposeQuantitative susceptibility mapping (QSM) has surfaced as a promising non-invasive quantitative biomarker that provides information about tissue composition and microenvironment.
Hyungseok Jang+12 more
doaj +1 more source
The presence of iron is essential for many biological processes in the body. But sometimes, for various reasons, the amount of iron deposition in different areas of the brain increases, which leads to problems related to the nervous system.
Farzaneh Nikparast+4 more
doaj +1 more source
BackgroundR2* relaxometry and quantitative susceptibility mapping can be combined to distinguish between microstructural changes and iron deposition in white matter.
Yuya Kano+11 more
doaj +1 more source
Ex-vivo quantitative susceptibility mapping of human brain hemispheres. [PDF]
Ex-vivo brain quantitative susceptibility mapping (QSM) allows investigation of brain characteristics at essentially the same point in time as histopathologic examination, and therefore has the potential to become an important tool for determining the ...
Arnold M Evia+8 more
doaj +1 more source