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Neuroimaging of Parkinson's disease by quantitative susceptibility mapping
Parkinson's disease (PD) is a common neurodegenerative disease, and apart from a few rare genetic causes, its pathogenesis remains largely unclear. Recent scientific interest has been captured by the involvement of iron biochemistry and the disruption of
Xiaojun Guan +5 more
doaj +5 more sources
The brain tissue phase contrast in MRI sequences reflects the spatial distributions of multiple substances, such as iron, myelin, calcium, and proteins. These substances with paramagnetic and diamagnetic susceptibilities often colocalize in one voxel in ...
Zhenghao Li +8 more
doaj +2 more sources
MoDL-QSM: Model-based deep learning for quantitative susceptibility mapping [PDF]
Quantitative susceptibility mapping (QSM) has demonstrated great potential in quantifying tissue susceptibility in various brain diseases. However, the intrinsic ill-posed inverse problem relating the tissue phase to the underlying susceptibility ...
Ruimin Feng +10 more
doaj +2 more sources
Thin slab quantitative susceptibility mapping
AbstractPurposeSusceptibility maps reconstructed from thin slabs may suffer underestimation due to background‐field removal imperfections near slab boundaries and the increased difficulty of solving a 3D‐inversion problem with reduced support, particularly in the direction of the main magnetic field.
Nashwan Naji, Alan Wilman
openaire +3 more sources
Quantitative susceptibility mapping in atypical Parkinsonisms
Background and purpose: Differential diagnosis between Parkinson's disease (PD) and Atypical Parkinsonisms, mainly Progressive Supranuclear Palsy (PSP) and Multiple System Atrophy (MSA), remains challenging. The low sensitivity of macroscopic findings at
Sonia Mazzucchi +9 more
doaj +3 more sources
Insights From Quantitative Susceptibility Mapping: An Umbrella Review of Multiple Sclerosis [PDF]
Background and Aims Multiple sclerosis (MS) is a chronic inflammatory disease of the central nervous system characterized by demyelination and neurodegeneration. Conventional MRI techniques lack specificity for detecting subtle pathological changes, such
Sadegh Ghaderi +2 more
doaj +2 more sources
A sensitive and accurate imaging technique capable of tracking the disease progression of Alzheimer's Disease (AD) driven amnestic dementia would be beneficial.
Maruf Ahmed +6 more
doaj +2 more sources
Quantitative Susceptibility Mapping in Parkinson's Disease.
BackgroundQuantitative susceptibility mapping (QSM) and R2* relaxation rate mapping have demonstrated increased iron deposition in the substantia nigra of patients with idiopathic Parkinson's disease (PD).
Christian Langkammer +16 more
doaj +3 more sources
QSMART: Quantitative susceptibility mapping artifact reduction technique
Purpose: Quantitative susceptibility mapping (QSM) is a novel MR technique that allows mapping of tissue susceptibility values from MR phase images. QSM is an ill-conditioned inverse problem, and although several methods have been proposed in the field ...
Negin Yaghmaie +2 more
exaly +3 more sources
Quantitative susceptibility mapping of brain iron in adult ADHD [PDF]
BackgroundAttention-deficit/hyperactivity disorder (ADHD) is a neurodevelopmental condition that frequently persists into adulthood and is linked to alterations in fronto-striatal circuitry and dopaminergic signaling. Brain iron is essential for dopamine
Marcel Schulze +12 more
doaj +2 more sources

