Results 81 to 90 of about 181,158 (299)

Free breathing three-dimensional cardiac quantitative susceptibility mapping for differential cardiac chamber blood oxygenation – initial validation in patients with cardiovascular disease inclusive of direct comparison to invasive catheterization

Journal of Cardiovascular Magnetic Resonance, 2019
Background Differential blood oxygenation between left (LV) and right ventricles (RV; ΔSaO2) is a key index of cardiac performance; LV dysfunction yields increased RV blood pool deoxygenation.
Yan Wen, Jonathan W. Weinsaft, Thanh D. Nguyen, Zhe Liu, Evelyn M. Horn, Harsimran Singh, Jonathan Kochav, Sarah Eskreis-Winkler, Kofi Deh, Jiwon Kim, Martin R. Prince, Yi Wang, Pascal Spincemaille   +12 more
doaj   +1 more source

Weak‐harmonic regularization for quantitative susceptibility mapping [PDF]

Magnetic Resonance in Medicine, 2018
PurposeBackground‐field removal is a crucial preprocessing step for quantitative susceptibility mapping (QSM). Remnants from this step often contaminate the estimated local field, which in turn leads to erroneous tissue‐susceptibility reconstructions.
Carlos Milovic, Berkin Bilgic, Bo Zhao, Christian Langkammer, Cristian Tejos, Julio Acosta‐Cabronero   +5 more
openaire   +4 more sources

Quantitative susceptibility mapping shows lower brain iron content in children with attention‐deficit hyperactivity disorder

Human Brain Mapping, 2022
To investigate the feasibility of quantitative susceptibility mapping in children with attention‐deficit hyperactivity disorder (ADHD), 53 children with ADHD aged 5–16 years were prospectively selected as the study group and 49 healthy children matched ...
Shilong Tang, Guanping Zhang, Qiying Ran, Lisha Nie, Xianfan Liu, Zhengxia Pan, Ling He   +6 more
semanticscholar   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Quantitative susceptibility mapping in multiple sclerosis: A systematic review and meta-analysis

NeuroImage: Clinical
Highlights • Systematic review on magnetic susceptibility values (QSM values) in MS.• Compared to controls, QSM values are increased in the basal ganglia but reduced in the thalamus.• QSM values of white matter lesions change over time, increasing first,
Cuici Voon, Tun Wiltgen, B. Wiestler, Sarah Schlaeger, Mark Mühlau   +4 more
semanticscholar   +1 more source

PARK(ing) time–How park deficiency affects the biological clock in a Drosophila model of Parkinson's disease

FEBS Letters, EarlyView.
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara, Kinga Skoczek, Elzbieta Pyza, Milena Damulewicz   +3 more
wiley   +1 more source

Advances in neuroimaging applications of quantitative susceptibility mapping

Meta-Radiology
This review article delves into the advancements of quantitative susceptibility mapping (QSM) in neuroimaging, highlighting its utility in detecting and quantifying magnetic susceptibility differences in tissues, particularly for paramagnetic substances ...
Shuxin Ma, Wencan Fu, Chao Chai, Huiying Wang, Ke Lv, Chenxi Zhao, E. Mark Haacke, Sagar Buch, Shuang Xia   +8 more
doaj   +1 more source

Morphometric imaging and quantitative susceptibility mapping as complementary tools in the diagnosis of parkinsonisms

European Journal of Neurology, 2022
In the quest for in vivo diagnostic biomarkers to discriminate Parkinson's disease (PD) from progressive supranuclear palsy (PSP) and multiple system atrophy (MSA, mainly p phenotype), many advanced magnetic resonance imaging (MRI) techniques have been ...
S. Mazzucchi, E. Del Prete, M. Costagli, D. Frosini, D. Paoli, G. Migaleddu, P. Cecchi, G. Donatelli, R. Morganti, G. Siciliano, M. Cosottini, R. Ceravolo   +11 more
semanticscholar   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Associations of quantitative susceptibility mapping with Alzheimer’s disease clinical and imaging markers

NeuroImage, 2020
Altered iron metabolism has been hypothesized to be associated with Alzheimer’s disease pathology, and prior work has shown associations between iron load and beta amyloid plaques.
P. Cogswell, H. Wiste, M. Senjem, J. Gunter, S. Weigand, C. Schwarz, A. Arani, T. Therneau, V. Lowe, D. Knopman, H. Botha, J. Graff‐Radford, David T. Jones, K. Kantarci, P. Vemuri, B. Boeve, M. Mielke, R. Petersen, C. Jack   +18 more
semanticscholar   +1 more source