Results 61 to 70 of about 181,158 (299)

Automated adaptive preconditioner for quantitative susceptibility mapping [PDF]

Magnetic Resonance in Medicine, 2019
PurposeTo develop an automated adaptive preconditioner for QSM reconstruction with improved susceptibility quantification accuracy and increased image quality.Theory and MethodsThe total field was used to rapidly produce an approximate susceptibility map, which was then averaged and trended over binning to generate a spatially varying distribution ...
Zhe Liu, Yan Wen, Pascal Spincemaille, Shun Zhang, Yihao Yao, Thanh D. Nguyen, Yi Wang   +6 more
openaire   +2 more sources

Quantitative Susceptibility Mapping Reveals an Association between Brain Iron Load and Depression Severity

Frontiers in Human Neuroscience, 2017
Previous studies have detected abnormal serum ferritin levels in patients with depression; however, the results have been inconsistent. This study used quantitative susceptibility mapping (QSM) for the first time to examine brain iron concentration in ...
Shun Yao, Yi Zhong, Yuhao Xu, Jiasheng Qin, Ningning Zhang, Xiaolan Zhu, Yuefeng Li   +6 more
doaj   +1 more source

Imaging the Centromedian Thalamic Nucleus Using Quantitative Susceptibility Mapping

Frontiers in Human Neuroscience, 2020
The centromedian (CM) nucleus is an intralaminar thalamic nucleus that is considered as a potentially effective target of deep brain stimulation (DBS) and ablative surgeries for the treatment of multiple neurological and psychiatric disorders.
Jun Li, Yufei Li, Lorenzo Gutierrez, Wenying Xu, Yiwen Wu, Chunlei Liu, Chunlei Liu, Dianyou Li, Bomin Sun, Chencheng Zhang, Hongjiang Wei   +10 more
doaj   +1 more source

Sensitivity of Quantitative Susceptibility Mapping for Clinical Research in Deep Gray Matter

Human Brain Mapping
Quantitative susceptibility mapping (QSM) is an advanced MRI technique for assessing iron, calcium, and myelin tissue levels based on magnetic susceptibility. QSM consists of multiple processing steps, with various choices for each step.
Fahad Salman, Abhisri Ramesh, T. Jochmann, Mirjam Prayer, Ademola Adegbemigun, Jack A. Reeves, Gregory E. Wilding, Junghun Cho, D. Jakimovski, N. Bergsland, M. Dwyer, R. Zivadinov, F. Schweser   +12 more
semanticscholar   +1 more source

Disease correlates of rim lesions on quantitative susceptibility mapping in multiple sclerosis

Scientific Reports, 2021
Quantitative susceptibility mapping (QSM), an imaging technique sensitive to brain iron, has been used to detect paramagnetic rims of iron-laden active microglia and macrophages in a subset of multiple sclerosis (MS) lesions, known as rim+ lesions, that ...
M. Marcille, S. Rúa, C. Tyshkov, A. Jaywant, J. Comunale, U. Kaunzner, Nancy M Nealon, J. Perumal, L. Zexter, N. Zinger, O. Bruvik, Yi Wang, E. Sweeney, Amy Kuceyeski, Thanh D. Nguyen, S. Gauthier   +15 more
semanticscholar   +1 more source

Quantitative susceptibility mapping is more sensitive and specific than phase imaging in detecting chronic active multiple sclerosis lesion rims: pathological validation

Brain Communications
Quantitative susceptibility mapping and phase imaging are used to identify multiple sclerosis lesions with paramagnetic rims that slowly expand over time and are associated with earlier progression to disability, decreased brain volume and increased ...
K. Gillen, Thanh D. Nguyen, A. Dimov, I. Kovanlikaya, Ha Luu, E. Demmon, Daniel M. Markowitz, F. Bagnato, D. Pitt, S. Gauthier, Yi Wang   +10 more
semanticscholar   +1 more source

Iron deposition in Parkinson’s disease by quantitative susceptibility mapping

BMC Neuroscience, 2019
Background Patients with Parkinson’s disease (PD) have elevated levels of brain iron, especially in the nigrostriatal dopaminergic system. The purpose of this study was to evaluate the iron deposition in the substantia nigra (SN) and other deep gray ...
Qiqi Chen, Yiting Chen, Yue Zhang, Furu Wang, Hongchang Yu, Caiyuan Zhang, Zhen Jiang, Weifeng Luo   +7 more
doaj   +1 more source

Biophysical contrast sources for magnetic susceptibility and R2* mapping: A combined 7 Tesla, mass spectrometry and electron paramagnetic resonance study

NeuroImage
Iron is the most abundant trace metal in the human brain and consistently shown elevated in prevalent neurological disorders. Because of its paramagnetism, brain iron can be assessed in vivo by quantitative MRI techniques such as R2* mapping and ...
Fábio Seiji Otsuka, Maria Concepción Garcia Otaduy, Roberta Diehl Rodriguez, Christian Langkammer, Jeam Haroldo Oliveira Barbosa, Carlos Ernesto Garrido Salmon   +5 more
doaj   +1 more source

Ex-vivo quantitative susceptibility mapping of human brain hemispheres.

PLoS ONE, 2017
Ex-vivo brain quantitative susceptibility mapping (QSM) allows investigation of brain characteristics at essentially the same point in time as histopathologic examination, and therefore has the potential to become an important tool for determining the ...
Arnold M Evia, Aikaterini Kotrotsou, Ashish A Tamhane, Robert J Dawe, Alifiya Kapasi, Sue E Leurgans, Julie A Schneider, David A Bennett, Konstantinos Arfanakis   +8 more
doaj   +1 more source

The increased iron deposition of the gray matter over the whole brain in chronic migraine: An exploratory quantitative susceptibility mapping study

Molecular Pain, 2022
Background Prior studies identified iron deposition in deep brain nuclei and the periaqueductal gray matter region in chronic migraine, and less is known about the cerebral iron deposition over the whole cerebral gray matter in CM.
Zhiye Chen, He Zhao, Xiaoyan Chen, Mengqi Liu, Xin Li, Lin Ma, Shengyuan Yu   +6 more
doaj   +1 more source