Results 51 to 60 of about 181,158 (299)

Quantitative susceptibility mapping of the midbrain in Parkinson's disease [PDF]

Movement Disorders, 2015
AbstractBackgroundParkinson's disease (PD) is marked pathologically by dopamine neuron loss and iron overload in the substantia nigra pars compacta. Midbrain iron content is reported to be increased in PD based on magnetic resonance imaging (MRI) R2* changes.
Guangwei, Du, Tian, Liu, Mechelle M, Lewis, Lan, Kong, Yi, Wang, James, Connor, Richard B, Mailman, Xuemei, Huang   +7 more
openaire   +2 more sources

Decompose quantitative susceptibility mapping (QSM) to sub-voxel diamagnetic and paramagnetic components based on gradient-echo MRI data

NeuroImage, 2021
Purpose: A method named DECOMPOSE-QSM is developed to decompose bulk susceptibility measured with QSM into sub-voxel paramagnetic and diamagnetic components based on a three-pool complex signal model.
Jingjia Chen, N. Gong, K. Chaim, M. Otaduy, Chunlei Liu   +4 more
semanticscholar   +1 more source

Brain Nucleus Changes in Cognitive Disorders: Examining By the Quantitative Susceptibility Mapping (QSM) Technique [PDF]

Iranian Journal of Medical Physics
Introduction: Iron deposition is vital for damaging neurons and causing different cognitive disorders. Today, using the quantitative susceptibility mapping (QSM) technique, iron deposits in other brain areas can be assessed and measured. This study aimed
Farzaneh Nikparast, Ali Shoeibi, Shabnam Niroumand, Hossein Akbari-Lalimi, Hoda Zare   +4 more
doaj   +1 more source

msQSM: Morphology-based self-supervised deep learning for quantitative susceptibility mapping

NeuroImage, 2023
Quantitative susceptibility mapping (QSM) has been applied to the measurement of iron deposition and the auxiliary diagnosis of neurodegenerative disease. There still exists a dipole inversion problem in QSM reconstruction.
Junjie He, Yunsong Peng, Bangkang Fu, Yuemin Zhu, Lihui Wang, Rongpin Wang   +5 more
doaj   +1 more source

Rapid multi-orientation quantitative susceptibility mapping [PDF]

NeuroImage, 2016
Three-dimensional gradient echo (GRE) is the main workhorse sequence used for susceptibility weighted imaging (SWI), quantitative susceptibility mapping (QSM), and susceptibility tensor imaging (STI). Achieving optimal phase signal-to-noise ratio requires late echo times, thus necessitating a long repetition time (TR).
Berkin Bilgic, Luke Xie, Russell Dibb, Christian Langkammer, Aysegul Mutluay, Huihui Ye, Jonathan R. Polimeni, Jean Augustinack, Chunlei Liu 0004, Lawrence L. Wald, Kawin Setsompop   +10 more
openaire   +4 more sources

Evaluation of iron overload in nigrosome 1 via quantitative susceptibility mapping as a progression biomarker in prodromal stages of synucleinopathies

NeuroImage, 2022
Idiopathic rapid eye movement (REM) sleep behavior disorder (iRBD) is a prodromal stage of α-synucleinopathies, such as Parkinson's disease (PD), which are characterized by the loss of dopaminergic neurons in substantia nigra, associated with abnormal ...
M. Lancione, G. Donatelli, E. Prete, Nicole Campese, D. Frosini, Matteo Cencini, M. Costagli, L. Biagi, Giacomo Lucchi, M. Tosetti, M. Godani, Dario Arnaldi, M. Terzaghi, F. Provini, C. Pacchetti, P. Cortelli, E. Bonanni, R. Ceravolo, M. Cosottini   +18 more
semanticscholar   +1 more source

R2* and quantitative susceptibility mapping in deep gray matter of 498 healthy controls from 5 to 90 years

Human Brain Mapping, 2021
Putative MRI markers of iron in deep gray matter have demonstrated age related changes during discrete periods of healthy childhood or adulthood, but few studies have included subjects across the lifespan.
S. Treit, Nashwan Naji, P. Seres, Julia Rickard, Emily Stolz, A. Wilman, C. Beaulieu   +6 more
semanticscholar   +1 more source

Rapid automated liver quantitative susceptibility mapping [PDF]

Journal of Magnetic Resonance Imaging, 2019
BackgroundAccurate measurement of the liver iron concentration (LIC) is needed to guide iron‐chelating therapy for patients with transfusional iron overload. In this work, we investigate the feasibility of automated quantitative susceptibility mapping (QSM) to measure the LIC.PurposeTo develop a rapid, robust, and automated liver QSM for clinical ...
Ramin Jafari, Sujit Sheth, Pascal Spincemaille, Thanh D. Nguyen, Martin R. Prince, Yan Wen, Yihao Guo, Kofi Deh, Zhe Liu, Daniel Margolis, Gary M. Brittenham, Andrea S. Kierans, Yi Wang   +12 more
openaire   +2 more sources

Brain iron deposition and cognitive decline in patients with cerebral small vessel disease : a quantitative susceptibility mapping study

Alzheimer's Research & Therapy
Quantitative susceptibility mapping (QSM) can study the susceptibility values of brain tissue which allows for noninvasive examination of local brain iron levels in both normal and pathological conditions. Our study compares brain iron deposition in gray
Yian Gao, Changhu Liang, Qihao Zhang, Hangwei Zhuang, Chaofan Sui, Nan Zhang, Mengmeng Feng, Haotian Xin, Lingfei Guo, Yi Wang   +9 more
semanticscholar   +1 more source

Quantitative susceptibility mapping vs. phase imaging to identify multiple sclerosis iron rim lesions with demyelination

Journal of Neuroimaging, 2022
To compare quantitative susceptibility mapping (QSM) and high‐pass‐filtered (HPF) phase imaging for (1) identifying chronic active rim lesions with more myelin damage and (2) distinguishing patients with increased clinical disability in multiple ...
Weiyuan Huang, E. Sweeney, U. Kaunzner, Yi Wang, S. Gauthier, Thanh D. Nguyen   +5 more
semanticscholar   +1 more source