Results 301 to 310 of about 267,706 (322)

Quantitative Systems Pharmacology: An Overview

International Journal of pharma and Bio Sciences, 2023
Dr. Virendra Kushwaha, Dr. Pooja Agrawal, Dr. Vipul Shukla, Dr. Geeta Singh Rana   +3 more
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Quantitative Systems Pharmacology Development and Application in Neuroscience

Successful clinical development of therapeutics in neurology and psychiatry is challenging due to the complexity of the brain, the lack of validated surrogate markers and the nature of clinical assessments. On the other hand, tremendous advances have been made in unraveling the neurophysiology of the human brain thanks to technical developments in ...
openaire   +2 more sources

Using quantitative systems pharmacology for novel drug discovery

Expert Opinion on Drug Discovery, 2015
Over the past three decades, the predominant paradigm in drug discovery was designing selective ligands for a specific target to avoid unwanted side effects. However, in the last 5 years, the aim has shifted to take into account the biological network in which they interact.
openaire   +2 more sources

A framework for simplification of quantitative systems pharmacology models in clinical pharmacology

British Journal of Clinical Pharmacology, 2022
Abdallah Derbalah, Hesham S Al-Sallami, Chihiro Hasegawa   +2 more
exaly  

An introduction to quantitative systems pharmacology for chemical engineers

Physical Sciences Reviews
Abstract Quantitative systems pharmacology (QSP) is a discipline that integrates experimental and mathematical modelling practice to perform a variety of analysis in the pharmaceutical research and development space. As the pharma industry strives for leaner product development, reduction of time and costs, and the implementation of the ...
Roberto A. Abbiati, Cesar Pichardo
openaire   +1 more source

The convergence of pharmacometrics and quantitative systems pharmacology in pharmaceutical research and development

European Journal of Pharmaceutical Sciences, 2023
Amita Joshi, Saroja Ramanujan, Jin Y Jin   +2 more
exaly  

The application of quantitative histochemistry to the pharmacology of the nervous system

Biochemical Pharmacology, 1962
O H, LOWRY, J V, PASSONNEAU
openaire   +2 more sources

Recent applications of quantitative systems pharmacology and machine learning models across diseases

Journal of Pharmacokinetics and Pharmacodynamics, 2021
Sara Sadat Aghamiri, Tomáš Helikar
exaly  

The role of quantitative systems pharmacology in pharmacometrics and the scope of the journal

Journal of Pharmacokinetics and Pharmacodynamics, 2023
openaire   +2 more sources

Linear-In-Flux-Expressions Methodology: Toward a Robust Mathematical Framework for Quantitative Systems Pharmacology Simulators

Gene Regulation and Systems Biology, 2017
Sean T McQuade, Jeffrey S Barrett, Benedetto Piccoli   +2 more
exaly