Results 181 to 190 of about 20,185 (216)
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Anthropologischer Anzeiger, 2016
Heritability is a statistical measure, expressing the proportion of phenotypic variance that is explained by the genetic variance. Heritability of a given trait can vary in time and may differ between populations, which is inter alia associated with interactions and correlations between genotype and environment or population-specific differences ...
Krystyna Cieślik, Małgorzata Waszak
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Heritability is a statistical measure, expressing the proportion of phenotypic variance that is explained by the genetic variance. Heritability of a given trait can vary in time and may differ between populations, which is inter alia associated with interactions and correlations between genotype and environment or population-specific differences ...
Krystyna Cieślik, Małgorzata Waszak
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Heritability estimation of sex‐specific effects on human quantitative traits
Genetic Epidemiology, 2007AbstractRecent studies have suggested that sex‐specific genetic architecture could be because of the effects of autosomal genes that are differentially expressed in males and females. Yet, few studies have explored the effects of X‐linked genes on sex‐specific genetic architecture.
Lin Pan, Mark Abney, Carole Ober
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Statistical power and heritability in whole-genome association studies for quantitative traits
Meta Gene, 2021Abstract The genome-wide association studies (GWAS) have made many advances in identifying the underlying genetics of diseases and quantitative traits. Still, GWAS has major problems, such as the lack of justification for genetic variation and the inability to fully recognize the rare variants. Probably the next generation sequencing (NGS) technology
Shahrokh Ghovvati +2 more
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IS SURVIVAL TIME AFTER HEMORRHAGE A HERITABLE, QUANTITATIVE TRAIT?
Shock, 2008Enhancing survival to hemorrhage of both civilian and military patients is a major emphasis for trauma research. Previous observations in humans and outbred rats show differential survival to similar levels of hemorrhage. In an initial attempt to determine potential genetic components of such differential outcomes, survival time after a controlled ...
David G. Baer +7 more
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Heritabilities and quantitative trait loci for blood gases and blood pH in swine
Animal Genetics, 2009SummaryMaintaining pH and blood gases in a narrow range is essential to sustain normal biochemical reactions. Decreased oxygenation, poor tissue perfusion, disturbance to CO2 expiration, and shortage of HCO3− can lead to metabolic acidosis. This is a common situation in swine, and originates from a broad range of medical conditions.
Hermann Willems +5 more
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American Journal of Medical Genetics, 2002
AbstractDespite evidence for several chromosomal loci linked to schizophrenia, no susceptibility genes have been identified for the disorder. Using quantitative measures of phenotypic affection in place of clinical diagnostic categories or dichotomous classification of the affection status may be more effective in searching for susceptibility genes ...
Jouko Lönnqvist +8 more
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AbstractDespite evidence for several chromosomal loci linked to schizophrenia, no susceptibility genes have been identified for the disorder. Using quantitative measures of phenotypic affection in place of clinical diagnostic categories or dichotomous classification of the affection status may be more effective in searching for susceptibility genes ...
Jouko Lönnqvist +8 more
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Human Heredity, 1993
Methods to determine the proportion of variability manifested by a quantitative trait that is attributable to additive genetic effects are important tools for human population and statistical geneticists. Though traditional methods based on parent-offspring and sib-pair correlations have been well researched, they are being steadily supplanted or ...
M. A. Schork, Nicholas J. Schork
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Methods to determine the proportion of variability manifested by a quantitative trait that is attributable to additive genetic effects are important tools for human population and statistical geneticists. Though traditional methods based on parent-offspring and sib-pair correlations have been well researched, they are being steadily supplanted or ...
M. A. Schork, Nicholas J. Schork
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Principal Components of Heritability for High Dimension Quantitative Traits and General Pedigrees
Statistical Applications in Genetics and Molecular Biology, 2012For many complex disorders, genetically relevant disease definition is still unclear. For this reason, researchers tend to collect large numbers of items related directly or indirectly to the disease diagnostic. Since the measured traits may not be all influenced by genetic factors, researchers are faced with the problem of choosing which traits or ...
Oualkacha, Karim +4 more
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Quantitative genetics of cranial nonmetric traits in randombred mice: Heritability and etiology
American Journal of Physical Anthropology, 1986AbstractCheverud and Buikstra (1981) demonstrated a tendency for nonmetric traits representing the number of foramina to have lower heritabilities than those representing hyperstotic or hypostotic traits in a sample of rhesus macaques. Based on this observation, Cheverud and Buikstra hypothesize that differences in the heritability of the two sets of ...
Janet W. McGrath, Joan T. Richtsmeier
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Journal of Crop Improvement, 2018
Breeding efforts in cereal crops directed toward developing or improving end-use products of grain require assessment of existing phenotypic variance and an understanding of the genetic control of ...
Nikhil Y. Patil +7 more
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Breeding efforts in cereal crops directed toward developing or improving end-use products of grain require assessment of existing phenotypic variance and an understanding of the genetic control of ...
Nikhil Y. Patil +7 more
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