Results 21 to 30 of about 22,558 (261)

Transcriptome-wide association studies: recent advances in methods, applications and available databases

open access: yesCommunications Biology, 2023
Genome-wide association study has identified fruitful variants impacting heritable traits. Nevertheless, identifying critical genes underlying those significant variants has been a great task.
Jialin Mai   +4 more
doaj   +1 more source

Heritability and quantitative genetic divergence of serotiny, a fire-persistence plant trait [PDF]

open access: yesAnnals of Botany, 2014
Although it is well known that fire acts as a selective pressure shaping plant phenotypes, there are no quantitative estimates of the heritability of any trait related to plant persistence under recurrent fires, such as serotiny. In this study, the heritability of serotiny in Pinus halepensis is calculated, and an evaluation is made as to whether fire ...
Hernández-Serrano, Ana   +5 more
openaire   +5 more sources

Composition of the ileum microbiota is a mediator between the host genome and phosphorus utilization and other efficiency traits in Japanese quail (Coturnix japonica)

open access: yesGenetics Selection Evolution, 2022
Background Phosphorus is an essential nutrient in all living organisms and, currently, it is the focus of much attention due to its global scarcity, the environmental impact of phosphorus from excreta, and its low digestibility due to its storage in the ...
Valentin Haas   +5 more
doaj   +1 more source

Understanding Disease Susceptibility through Population Genomics [PDF]

open access: yesGenomics & Informatics, 2012
Genetic epidemiology studies have established that the natural variation of gene expression profiles is heritable and has genetic bases. A number of proximal and remote DNA variations, known as expression quantitative trait loci (eQTLs), that are ...
Seonggyun Han, Junnam Lee, Sangsoo Kim
doaj   +1 more source

An Effective Method to Identify Heritable Components from Multivariate Phenotypes.

open access: yesPLoS ONE, 2015
Multivariate phenotypes may be characterized collectively by a variety of low level traits, such as in the diagnosis of a disease that relies on multiple disease indicators. Such multivariate phenotypes are often used in genetic association studies.
Jiangwen Sun, Henry R Kranzler, Jinbo Bi
doaj   +1 more source

Developmental and genetic effects on behavioral and life‐history traits in a field cricket

open access: yesEcology and Evolution, 2019
A fundamental goal of evolutionary ecology is to identify the sources underlying trait variation on which selection can act. Phenotypic variation will be determined by both genetic and environmental factors, and adaptive phenotypic plasticity is expected
Tina W. Wey   +2 more
doaj   +1 more source

DNA methylation at quantitative trait loci (mQTLs) varies with cell type and nonheritable factors and may improve breast cancer risk assessment

open access: yesnpj Precision Oncology, 2023
To individualise breast cancer (BC) prevention, markers to follow a person’s changing environment and health extending beyond static genetic risk scores are required.
Chiara Herzog   +10 more
doaj   +1 more source

A major QTL controls susceptibility to spinal curvature in the curveback guppy

open access: yesBMC Genetics, 2011
Background Understanding the genetic basis of heritable spinal curvature would benefit medicine and aquaculture. Heritable spinal curvature among otherwise healthy children (i.e.
Dreyer Christine   +6 more
doaj   +1 more source

Biased estimators of quantitative trait locus heritability and location in interval mapping [PDF]

open access: yesHeredity, 2005
In many empirical studies, it has been observed that genome scans yield biased estimates of heritability, as well as genetic effects. It is widely accepted that quantitative trait locus (QTL) mapping is a model selection procedure, and that the overestimation of genetic effects is the result of using the same data for model selection as estimation of ...
M, Bogdan, R W, Doerge
openaire   +2 more sources

Gene expression genetics of the striatum of Diversity Outbred mice

open access: yesScientific Data, 2023
Brain transcriptional variation is a heritable trait that mediates complex behaviors, including addiction. Expression quantitative trait locus (eQTL) mapping reveals genomic regions harboring genetic variants that influence transcript abundance.
Vivek M. Philip   +5 more
doaj   +1 more source

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