Results 41 to 50 of about 55,223 (296)

Empirically derived phenotypic subgroups – qualitative and quantitative trait analyses [PDF]

open access: yes, 2003
BACKGROUND. The Framingham Heart Study has contributed a great deal to advances in medicine. Most of the phenotypes investigated have been univariate traits (quantitative or qualitative).
Farrell, John   +6 more
core   +3 more sources

Genetic analysis of genome-scale recombination rate evolution in house mice. [PDF]

open access: yesPLoS Genetics, 2011
The rate of meiotic recombination varies markedly between species and among individuals. Classical genetic experiments demonstrated a heritable component to population variation in recombination rate, and specific sequence variants that contribute to ...
Beth L Dumont, Bret A Payseur
doaj   +1 more source

The Stabilizing Effect Of Intraspecific Genetic Variation On Population Dynamics In Novel And Ancestral Habitats [PDF]

open access: yes, 2009
Recent studies show that intraspecific genetic variation in asexual species may have large effects on community and ecosystem functions, increasing their stability, productivity, and species richness.
Agashe, Deepa
core   +1 more source

Biased estimators of quantitative trait locus heritability and location in interval mapping [PDF]

open access: yesHeredity, 2005
In many empirical studies, it has been observed that genome scans yield biased estimates of heritability, as well as genetic effects. It is widely accepted that quantitative trait locus (QTL) mapping is a model selection procedure, and that the overestimation of genetic effects is the result of using the same data for model selection as estimation of ...
M, Bogdan, R W, Doerge
openaire   +2 more sources

Quantitative genetic analysis deciphers the impact of cis and trans regulation on cell-to-cell variability in protein expression levels.

open access: yesPLoS Genetics, 2020
Identifying the factors that shape protein expression variability in complex multi-cellular organisms has primarily focused on promoter architecture and regulation of single-cell expression in cis.
Michael D Morgan   +5 more
doaj   +1 more source

Accurate Genomic Prediction Of Human Height [PDF]

open access: yes, 2017
We construct genomic predictors for heritable and extremely complex human quantitative traits (height, heel bone density, and educational attainment) using modern methods in high dimensional statistics (i.e., machine learning).
Avery, Steven G.   +5 more
core   +1 more source

Cholesteatoma and family history: An international survey [PDF]

open access: yes, 2020
Objective To explore the relative frequency of a family history of cholesteatoma in patients with known cholesteatoma, and whether bilateral disease or earlier diagnosis is more likely in those with a family history.
Clark, Allan   +6 more
core   +1 more source

Heritability of quantitative autism spectrum traits in adults: A family‐based study

open access: yesAutism Research, 2021
AbstractAutism spectrum disorder (ASD) comprises a multi‐dimensional set of quantitative behavioral traits expressed along a continuum in autistic and neurotypical individuals. ASD diagnosis—a dichotomous trait—is known to be highly heritable and has been used as the phenotype for most ASD genetic studies.
Sara C. Taylor   +18 more
openaire   +3 more sources

A stable and major QTL region on chromosome 2 conditions pod shape in cultivated peanut (Arachis hyopgaea L.)

open access: yesJournal of Integrative Agriculture, 2023
Peanut pod shape is a heritable trait which affects the market acceptance of in-shell peanut products. In order to determine the genetic control of pod shape, six component traits of pod shape (pod length, pod width, pod length/width ratio, pod roundness,
Sheng-zhong ZHANG   +11 more
doaj   +1 more source

A Testis‐Specific Aralkylamine N‐Acetyltransferase Regulates Dimorphic Sperm Function and Male Fertility in Moths

open access: yesAdvanced Science, EarlyView.
We identify a Lepidoptera‐conserved testis‐specific arylalkylamine N‐acetyltransferase (LTNAT) that governs male moth fertility via a novel mechanism. LTNAT loss disrupts eupyrene sperm mitochondrial derivatives and impairs apyrene sperm motility, offering a safe molecular target for innovative pesticides and genetic pest control.
Hao Sun   +5 more
wiley   +1 more source

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