Biased estimators of quantitative trait locus heritability and location in interval mapping [PDF]
In many empirical studies, it has been observed that genome scans yield biased estimates of heritability, as well as genetic effects. It is widely accepted that quantitative trait locus (QTL) mapping is a model selection procedure, and that the overestimation of genetic effects is the result of using the same data for model selection as estimation of ...
M, Bogdan, R W, Doerge
openaire +2 more sources
The efficiency of mapping of quantitative trait loci using cofactor analysis in half-sib design [PDF]
This simulation study was designed to study the power and type I error rate in QTL mapping using cofactor analysis in half-sib designs. A number of scenarios were simulated with different power to identify QTL by varying family size, heritability, QTL ...
Guldbrandtsen Bernt +14 more
core +1 more source
EFFECT OF SELECTION ON HERITABILITY AND GENETIC CORRELATION OF TWO QUANTITATIVE TRAITS IN MICE [PDF]
The effects of different intensities of single trait directional selection on the heritability and genetic correlation of two quantitative traits in random mating populations of mice were observed during 14 generations. The initial population was divided at random into five groups (A, B, C, D and E).
T K, Cheung, R J, Parker
openaire +2 more sources
Identification of Quantitative Trait Loci Determining Vegetative Growth Traits in Coffea canephor
Recently the use of molecular markers has been successfully applied for some crops. For coffee, new opportunities have been opened since Nestlé R&D Centre in collaboration with ICCRI completed the first genetic map of Coffea canephora.
Priyono Priyono +2 more
doaj +1 more source
Gene expression genetics of the striatum of Diversity Outbred mice
Brain transcriptional variation is a heritable trait that mediates complex behaviors, including addiction. Expression quantitative trait locus (eQTL) mapping reveals genomic regions harboring genetic variants that influence transcript abundance.
Vivek M. Philip +5 more
doaj +1 more source
Gene and QTL detection in a three-way barley cross under selection by a mixed model with kinship information using SNPs [PDF]
Quantitative trait locus (QTL) detection is commonly performed by analysis of designed segregating populations derived from two inbred parental lines, where absence of selection, mutation and genetic drift is assumed.
Casas, Ana M. +31 more
core +1 more source
Genetic analysis of genome-scale recombination rate evolution in house mice. [PDF]
The rate of meiotic recombination varies markedly between species and among individuals. Classical genetic experiments demonstrated a heritable component to population variation in recombination rate, and specific sequence variants that contribute to ...
Beth L Dumont, Bret A Payseur
doaj +1 more source
Common DNA markers can account for more than half of the genetic influence on cognitive abilities [PDF]
For nearly a century, twin and adoption studies have yielded substantial estimates of heritability for cognitive abilities, although it has proved difficult for genomewide-association studies to identify the genetic variants that account for this ...
Meaburn, Emma L +21 more
core +1 more source
Identifying the factors that shape protein expression variability in complex multi-cellular organisms has primarily focused on promoter architecture and regulation of single-cell expression in cis.
Michael D Morgan +5 more
doaj +1 more source
Insight into the genetic components of community genetics: QTL mapping of insect association in a fast-growing forest tree [PDF]
Identifying genetic sequences underlying insect associations on forest trees will improve the understanding of community genetics on a broad scale. We tested for genomic regions associated with insects in hybrid poplar using quantitative trait loci (QTL)
Katalin Tuba (486875) +24 more
core +2 more sources

