Results 41 to 50 of about 3,521,649 (161)

Heritability and tissue specificity of expression quantitative trait loci.

PLoS Genetics, 2006
Variation in gene expression is heritable and has been mapped to the genome in humans and model organisms as expression quantitative trait loci (eQTLs). We applied integrated genome-wide expression profiling and linkage analysis to the regulation of gene
Enrico Petretto, Jonathan Mangion, Nicholas J Dickens, Stuart A Cook, Mande K Kumaran, Han Lu, Judith Fischer, Henrike Maatz, Vladimir Kren, Michal Pravenec, Norbert Hubner, Timothy J Aitman   +11 more
doaj   +1 more source

Environmental coupling of selection and heritability limits evolution [PDF]

, 2006
There has recently been great interest in applying theoretical quantitative genetic models to empirical studies of evolution in wild populations. However, while classical models assume environmental constancy, most natural populations exist in variable ...
T H Clutton-Brock, D W Coltman, Pemberton J. M, Coltman, D. W., J. G. Pilkington, A. J. Wilson, Pemberton, J. M., D. W. Coltman, J G Pilkington, L E B Kruuk, Mifsud, D. V., Coltman D. W, J. M. Pemberton, D V Mifsud, D. V. Mifsud, Clutton-Brock T. H, Pilkington, J. G., Pilkington J. G, Wilson, A. J., Kruuk, L. E. B., A J Wilson, L. E. B. Kruuk, Clutton-Brock, T. H., T. H. Clutton-brock, Wilson A. J, Mifsud D. V, Kruuk L. E. B, J M Pemberton   +27 more
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Identifying quantitative trait loci for lodging-associated traits in the wheat doubled-haploid population Avalon × Cadenza [PDF]

, 2021
Lodging affects grain quality and grain yield in wheat (Triticum aestivum L.) and is difficult to breed for because its sporadic incidence and laborious protocols to measure lodging traits. Thus, developing molecular markers for these traits can increase
Sukumaran, Sivakumar, Piñera-Chavez, Francisco J., Berry, Peter M., Foulkes, Michael J., Reynolds, Matthew P., Foulkes, J., Piñera Chavez, F.J, Berry, P.M., Sukumaran, S., Reynolds, M.P.   +9 more
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DNA methylation at quantitative trait loci (mQTLs) varies with cell type and nonheritable factors and may improve breast cancer risk assessment

npj Precision Oncology, 2023
To individualise breast cancer (BC) prevention, markers to follow a person’s changing environment and health extending beyond static genetic risk scores are required.
Chiara Herzog, Allison Jones, Iona Evans, Michal Zikan, David Cibula, Nadia Harbeck, Nicoletta Colombo, Angelique Flöter Rådestad, Kristina Gemzell-Danielsson, Nora Pashayan, Martin Widschwendter   +10 more
doaj   +1 more source

A major QTL controls susceptibility to spinal curvature in the curveback guppy

BMC Genetics, 2011
Background Understanding the genetic basis of heritable spinal curvature would benefit medicine and aquaculture. Heritable spinal curvature among otherwise healthy children (i.e.
Dreyer Christine, Weigel Detlef, Ahmadi Roozbeh, Parent Jennifer, Christians Julian K, Gorman Kristen F, Breden Felix   +6 more
doaj   +1 more source

Identification of Quantitative Trait Loci Determining Vegetative Growth Traits in Coffea canephor

Coffee and Cocoa Research Journal, 2011
Recently the use of molecular markers has been successfully applied for some crops. For coffee, new opportunities have been opened since Nestlé R&D Centre in collaboration with ICCRI completed the first genetic map of Coffea canephora.
Priyono Priyono, Ucu Sumirat, Crouzillat Crouzillat   +2 more
doaj   +1 more source

Gene expression genetics of the striatum of Diversity Outbred mice

Scientific Data, 2023
Brain transcriptional variation is a heritable trait that mediates complex behaviors, including addiction. Expression quantitative trait locus (eQTL) mapping reveals genomic regions harboring genetic variants that influence transcript abundance.
Vivek M. Philip, Hao He, Michael C. Saul, Price E. Dickson, Jason A. Bubier, Elissa J. Chesler   +5 more
doaj   +1 more source

Empirically Derived Phenotypic Subgroups – Qualitative and Quantitative Trait Analyses [PDF]

, 2003
BACKGROUND. The Framingham Heart Study has contributed a great deal to advances in medicine. Most of the phenotypes investigated have been univariate traits (quantitative or qualitative).
Farrell, John, Ma, Qianli, Qianli Ma, Diego F Wyszynski, John Farrell, Panhuysen, Carolien I., Carolien I Panhuysen, Farrer, Lindsay A., Yip, Agustin, Wyszynski, Diego F., Lindsay A Farrer, Agustin Yip, Wilcox, Marsha A., Marsha A Wilcox   +13 more
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Genetic analysis of genome-scale recombination rate evolution in house mice. [PDF]

PLoS Genetics, 2011
The rate of meiotic recombination varies markedly between species and among individuals. Classical genetic experiments demonstrated a heritable component to population variation in recombination rate, and specific sequence variants that contribute to ...
Beth L Dumont, Bret A Payseur
doaj   +1 more source

The Heritability of Mating Behaviour in a Fly and Its Plasticity in Response to the Threat of Sperm Competition [PDF]

, 2014
Phenotypic plasticity is a key mechanism by which animals can cope with rapidly changeable environments, but the evolutionary lability of such plasticity remains unclear.
Price, TA, Bretman, Amanda J., Tom A R Price, Price, Tom A. R., Walling, CA, Anne Lizé, Lizé Anne, Bretman, A, Lizé, A, Bretman Amanda, Amanda Bretman, Bretman, Amanda, Craig A Walling, Price Tom A. R., Lize, Anne, Walling, Craig A., Walling Craig A., University of Liverpool, University of Leeds, School of Biological Sciences   +19 more
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