Results 51 to 60 of about 3,521,649 (161)

Heterochromatin is a quantitative trait associated with spontaneous epiallele formation

, 2021
first release of analysis code for the paper "Heterochromatin is a quantitative trait associated with spontaneous epiallele ...
Frank Johannes, Hosung Jang, Robert S. Piecyk, Rui Xiao, Yinwen Zhang, Ioanna Kakoulidou, Robert J. Schmitz   +6 more
core   +1 more source

Quantitative genetic analysis deciphers the impact of cis and trans regulation on cell-to-cell variability in protein expression levels.

PLoS Genetics, 2020
Identifying the factors that shape protein expression variability in complex multi-cellular organisms has primarily focused on promoter architecture and regulation of single-cell expression in cis.
Michael D Morgan, Etienne Patin, Bernd Jagla, Milena Hasan, Lluís Quintana-Murci, John C Marioni   +5 more
doaj   +1 more source

PCSK6 is associated with handedness in individuals with dyslexia [PDF]

, 2010
Approximately 90% of humans are right-handed. Handedness is a heritable trait, yet the genetic basis is not well understood. Here we report a genome-wide association study for a quantitative measure of relative hand skill in individuals with dyslexia ...
William M. Br, Morris, Andrew P., Morris, Andrew P, Monaco, Anthony P, Anthony P. Monaco, Richardson, Alex J, Alex J. Richardson, Joel B. Talcott, Silvia Paracchini, Richardson, Alex J., Stein, John, Monaco, Anthony P., William M. Brandler, Paracchini, Silvia, Stein, John F., John Stein, Ring, Susan M., Scerri, Thomas S, Talcott, Joel B., Talcott, Joel B, Brandler, William M., Ring, Susan M, Andrew P. Morris, Brandler, William M, Susan M. Ring, Thomas S. Scerri, Scerri, Thomas S., Paracchini, Silvia; id_orcid   +27 more
core   +1 more source

On Flexible finite polygenic models for multiple-trait evaluation [PDF]

, 2002
Finite polygenic models (FPM) might be an alternative to the infinitesimal model (TIM) for the genetic evaluation of pedigreed multiple-generation populations for multiple quantitative traits.
Bink, M.C.A.M.
core   +1 more source

A Latent Variable Approach to Multivariate Quantitative Trait Loci [PDF]

, 2010
A novel approach based on latent variable modelling is presented for the analysis of multivariate quantitative and qualitative trait loci. The approach is general in the sense that it enables the joint analysis of many kinds of quantitative and ...
Päivi Komulainen, Outi Savolainen, Mikko J. Sillanpää, Bob O'Hara   +3 more
core  

QTL detection and allelic effects for growth and fat traits in outbred pig populations [PDF]

, 2004
Quantitative trait loci (QTL) for growth and fatness traits have previously been identified on chromosomes 4 and 7 in several experimental pig populations.
Haley, CS, Visscher, Peter M, Chris S Haley, Nagamine, Y, Peter M. Visscher, Haley, Chris, Nagamine, Yoshitaka, Haley, Chris S, Peter M Visscher, Visscher Peter M, Visscher, PM, Chris S. Haley, Yoshitaka Nagamine, Visscher, Peter, Nagamine Yoshitaka, Haley Chris S   +15 more
core   +1 more source

A stable and major QTL region on chromosome 2 conditions pod shape in cultivated peanut (Arachis hyopgaea L.)

Journal of Integrative Agriculture, 2023
Peanut pod shape is a heritable trait which affects the market acceptance of in-shell peanut products. In order to determine the genetic control of pod shape, six component traits of pod shape (pod length, pod width, pod length/width ratio, pod roundness,
Sheng-zhong ZHANG, Xiao-hui HU, Fei-fei WANG, Ye CHU, Wei-qiang YANG, Sheng XU, Song WANG, Lan-rong WU, Hao-liang YU, Hua-rong MIAO, Chun FU, Jing CHEN   +11 more
doaj   +1 more source

Expression Quantitative Trait Loci in Equine Skeletal Muscle Reveals Heritable Variation in Metabolism and the Training Responsive Transcriptome

Frontiers in Genetics, 2019
While over ten thousand genetic loci have been associated with phenotypic traits and inherited diseases in genome-wide association studies, in most cases only a relatively small proportion of the trait heritability is explained and biological mechanisms ...
Gabriella Farries, Kenneth Bryan, Charlotte L. McGivney, Paul A. McGettigan, Katie F. Gough, John A. Browne, David E. MacHugh, David E. MacHugh, Lisa Michelle Katz, Emmeline W. Hill, Emmeline W. Hill   +10 more
doaj   +1 more source

Disease resistance in Atlantic salmon (Salmo salar): coinfection of the intracellular bacterial pathogen Piscirickettsia salmonis and the sea louse Caligus rogercresseyi. [PDF]

PLoS ONE, 2014
BACKGROUND: Naturally occurring coinfections of pathogens have been reported in salmonids, but their consequences on disease resistance are unclear. We hypothesized that 1) coinfection of Caligus rogercresseyi reduces the resistance of Atlantic salmon to
Jean Paul Lhorente, José A Gallardo, Beatriz Villanueva, María J Carabaño, Roberto Neira   +4 more
doaj   +1 more source

Linkage analysis of a model quantitative trait in humans: finger ridge count shows significant multivariate linkage to 5q14.1.

PLoS Genetics, 2007
The finger ridge count (a measure of pattern size) is one of the most heritable complex traits studied in humans and has been considered a model human polygenic trait in quantitative genetic analysis.
Sarah E Medland, Danuta Z Loesch, Bogdan Mdzewski, Gu Zhu, Grant W Montgomery, Nicholas G Martin   +5 more
doaj   +1 more source