Results 31 to 40 of about 22,558 (261)

EFFECT OF SELECTION ON HERITABILITY AND GENETIC CORRELATION OF TWO QUANTITATIVE TRAITS IN MICE [PDF]

open access: yesCanadian Journal of Genetics and Cytology, 1974
The effects of different intensities of single trait directional selection on the heritability and genetic correlation of two quantitative traits in random mating populations of mice were observed during 14 generations. The initial population was divided at random into five groups (A, B, C, D and E).
T K, Cheung, R J, Parker
openaire   +2 more sources

Identification of Quantitative Trait Loci Determining Vegetative Growth Traits in Coffea canephor

open access: yesCoffee and Cocoa Research Journal, 2011
Recently the use of molecular markers has been successfully applied for some crops. For coffee, new opportunities have been opened since Nestlé R&D Centre in collaboration with ICCRI completed the first genetic map of Coffea canephora.
Priyono Priyono   +2 more
doaj   +1 more source

Genetic analysis of genome-scale recombination rate evolution in house mice. [PDF]

open access: yesPLoS Genetics, 2011
The rate of meiotic recombination varies markedly between species and among individuals. Classical genetic experiments demonstrated a heritable component to population variation in recombination rate, and specific sequence variants that contribute to ...
Beth L Dumont, Bret A Payseur
doaj   +1 more source

Quantitative genetic analysis deciphers the impact of cis and trans regulation on cell-to-cell variability in protein expression levels.

open access: yesPLoS Genetics, 2020
Identifying the factors that shape protein expression variability in complex multi-cellular organisms has primarily focused on promoter architecture and regulation of single-cell expression in cis.
Michael D Morgan   +5 more
doaj   +1 more source

Heritability of quantitative autism spectrum traits in adults: A family‐based study

open access: yesAutism Research, 2021
AbstractAutism spectrum disorder (ASD) comprises a multi‐dimensional set of quantitative behavioral traits expressed along a continuum in autistic and neurotypical individuals. ASD diagnosis—a dichotomous trait—is known to be highly heritable and has been used as the phenotype for most ASD genetic studies.
Sara C. Taylor   +18 more
openaire   +3 more sources

A stable and major QTL region on chromosome 2 conditions pod shape in cultivated peanut (Arachis hyopgaea L.)

open access: yesJournal of Integrative Agriculture, 2023
Peanut pod shape is a heritable trait which affects the market acceptance of in-shell peanut products. In order to determine the genetic control of pod shape, six component traits of pod shape (pod length, pod width, pod length/width ratio, pod roundness,
Sheng-zhong ZHANG   +11 more
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Expression Quantitative Trait Loci in Equine Skeletal Muscle Reveals Heritable Variation in Metabolism and the Training Responsive Transcriptome

open access: yesFrontiers in Genetics, 2019
While over ten thousand genetic loci have been associated with phenotypic traits and inherited diseases in genome-wide association studies, in most cases only a relatively small proportion of the trait heritability is explained and biological mechanisms ...
Gabriella Farries   +10 more
doaj   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

open access: yesAging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

Disease resistance in Atlantic salmon (Salmo salar): coinfection of the intracellular bacterial pathogen Piscirickettsia salmonis and the sea louse Caligus rogercresseyi. [PDF]

open access: yesPLoS ONE, 2014
BACKGROUND: Naturally occurring coinfections of pathogens have been reported in salmonids, but their consequences on disease resistance are unclear. We hypothesized that 1) coinfection of Caligus rogercresseyi reduces the resistance of Atlantic salmon to
Jean Paul Lhorente   +4 more
doaj   +1 more source

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