Integration of genetics into a systems model of electrocardiographic traits using humanCVD BeadChip [PDF]
, 2012 <p>Background—Electrocardiographic traits are important, substantially heritable determinants of risk of arrhythmias and sudden cardiac death.</p> <p>Methods and Results—In this study, 3 population-based cohorts (n=10 526) genotyped ...
Adeniran, I. +24 more
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Developmental and genetic effects on behavioral and life‐history traits in a field cricket
Ecology and Evolution, 2019 A fundamental goal of evolutionary ecology is to identify the sources underlying trait variation on which selection can act. Phenotypic variation will be determined by both genetic and environmental factors, and adaptive phenotypic plasticity is expected
Tina W. Wey +2 more
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An Effective Method to Identify Heritable Components from Multivariate Phenotypes.
PLoS ONE, 2015 Multivariate phenotypes may be characterized collectively by a variety of low level traits, such as in the diagnosis of a disease that relies on multiple disease indicators. Such multivariate phenotypes are often used in genetic association studies.
Jiangwen Sun, Henry R Kranzler, Jinbo Bi
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A benign juvenile environment reduces the strength of antagonistic pleiotropy and genetic variation in the rate of senescence [PDF]
, 2015 The environment can play an important role in the evolution of senescence because the optimal allocation between somatic maintenance and reproduction depends on external factors influencing life expectancy.
Gonzalez G. +3 more
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npj Precision Oncology, 2023 To individualise breast cancer (BC) prevention, markers to follow a person’s changing environment and health extending beyond static genetic risk scores are required.
Chiara Herzog +10 more
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The Genetic Basis of Mutation Rate Variation in Yeast. [PDF]
, 2018 Mutations are the root source of genetic variation and underlie the process of evolution. Although the rates at which mutations occur vary considerably between species, little is known about differences within species, or the genetic and molecular basis ...
Bloom, Joshua S +2 more
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A major QTL controls susceptibility to spinal curvature in the
BMC Genetics, 2011 Background Understanding the genetic basis of heritable spinal curvature would benefit medicine and aquaculture. Heritable spinal curvature among otherwise healthy children (i.e.
Dreyer Christine +6 more
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Genetics of Intraspecies Variation in Avoidance Behavior Induced by a Thermal Stimulus in Caenorhabditis elegans. [PDF]
, 2015 Individuals within a species vary in their responses to a wide range of stimuli, partly as a result of differences in their genetic makeup. Relatively little is known about the genetic and neuronal mechanisms contributing to diversity of behavior in ...
Andolfatto, Peter +6 more
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EFFECT OF SELECTION ON HERITABILITY AND GENETIC CORRELATION OF TWO QUANTITATIVE TRAITS IN MICE [PDF]
Canadian Journal of Genetics and Cytology, 1974 The effects of different intensities of single trait directional selection on the heritability and genetic correlation of two quantitative traits in random mating populations of mice were observed during 14 generations. The initial population was divided at random into five groups (A, B, C, D and E).
T K, Cheung, R J, Parker
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Gene expression genetics of the striatum of Diversity Outbred mice
Scientific Data, 2023 Brain transcriptional variation is a heritable trait that mediates complex behaviors, including addiction. Expression quantitative trait locus (eQTL) mapping reveals genomic regions harboring genetic variants that influence transcript abundance.
Vivek M. Philip +5 more
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