Results 11 to 20 of about 3,366,415 (310)

Heritability and tissue specificity of expression quantitative trait loci. [PDF]

PLoS Genetics, 2006
Variation in gene expression is heritable and has been mapped to the genome in humans and model organisms as expression quantitative trait loci (eQTLs). We applied integrated genome-wide expression profiling and linkage analysis to the regulation of gene
Enrico Petretto, Jonathan Mangion, Nicholas J Dickens, Stuart A Cook, Mande K Kumaran, Han Lu, Judith Fischer, Henrike Maatz, Vladimir Kren, Michal Pravenec, Norbert Hubner, Timothy J Aitman   +11 more
doaj   +5 more sources

Niche construction in quantitative traits: heritability and response to selection

Proceedings of the Royal Society B: Biological Sciences, 2022
A central tenet of niche construction (NC) theory is that organisms can alter their environments in heritable and evolutionarily important ways, often altering selection pressures. We suggest that the physical changes niche constructors make to their environments may also alter trait heritability and the response of phenotypes to selection. This effect
Laurel Fogarty, Michael J. Wade
openaire   +3 more sources

Broad and Narrow Heritabilities of Quantitative Traits in a Founder Population [PDF]

The American Journal of Human Genetics, 2001
Estimation of the components of variance for a quantitative trait allows one to evaluate both the degree to which genetics influences the trait and the trait's underlying genetic architecture. For particular traits, the estimates also may have implications for discriminating between potential models of selection and for choosing an appropriate model ...
Abney, Mark, McPeek, Mary Sara, Ober, Carole   +2 more
openaire   +2 more sources

The role of heritability in mapping expression quantitative trait loci [PDF]

BMC Proceedings, 2007
Abstract Gene expression, as a heritable complex trait, has recently been used in many genome-wide linkage studies. The estimated overall heritability of each trait may be considered as evidence of a genetic contribution to the total phenotypic variation, which implies the possibility of mapping genome regions responsible for the gene ...
Huang, Song, Ballard, David, Zhao, Hongyu   +2 more
openaire   +2 more sources

Heritability Estimates of Some Quantitative Traits in Potatoes

Turkish Journal Of Field Crops, 2014
Broad-sense heritability (H) values of some quantitative traits in a potato population comprising 21 genotypes grown at Bornova, Izmir, Turkey during the 2013 and 2014 growing seasons were estimated by using the variance components analysis method. Based on the combined analysis of variance performed over two years, the following moderate to high level
OZTURK, Gulsum, YILDIRIM, Zihin
openaire   +5 more sources

Impulsivity is a heritable trait in rodents and associated with a novel quantitative trait locus on chromosome 1 [PDF]

Scientific Reports, 2020
AbstractImpulsivity describes the tendency to act prematurely without appropriate foresight and is symptomatic of a number of neuropsychiatric disorders. Although a number of genes for impulsivity have been identified, no study to date has carried out an unbiased, genome-wide approach to identify genetic markers associated with impulsivity in ...
Jupp, Bianca, Pitzoi, Silvia, Petretto, Enrico, Mar, Adam C, Oliver, Yolanda Pena, Jordan, Emily R, Taylor, Stephanie, Atanur, Santosh S, Srivastava, Prashant K, Saar, Kathrin, Hubner, Norbert, Sommer, Wolfgang H, Staehlin, Oliver, Spanagel, Rainer, Robinson, Emma S, Schumann, Gunter, Moreno, Margarita, Everitt, Barry J, Robbins, Trevor W, Aitman, Timothy J, Dalley, Jeffrey W   +20 more
openaire   +6 more sources

Explaining the heritability of an ecologically significant trait in terms of individual quantitative trait loci [PDF]

Biology Letters, 2011
Most natural populations display substantial genetic variation in behaviour, morphology, physiology, life history and the susceptibility to disease. A major challenge is to determine the contributions of individual loci to variation in complex traits.
Alison G, Scoville, Young Wha, Lee, John H, Willis, John K, Kelly   +3 more
openaire   +2 more sources

The quantitative genetic basis of sex ratio variation in Nasonia vitripennis : a QTL study [PDF]

, 2010
Our understanding of how natural selection should shape sex allocation is perhaps more developed than for any other trait. However, this understanding is not matched by our knowledge of the genetic basis of sex allocation.
Shuker, DM, West, SA, West, S. A., Knott, SA, Pannebakker, B.A., West, S.A., R. WATT, Watt, R, D. M. SHUKER, Shuker, D. M., S. A. KNOTT, Knott, S. A., Watt, R., Shuker, D.M., B. A. PANNEBAKKER, Pannebakker, B. A., Pannebakker, BA, Knott, S.A., S. A. WEST, Shuker, David Michael, Pannebakker, Bart   +20 more
core   +2 more sources

Trait-trait dynamic interaction: 2D-trait eQTL mapping for genetic variation study

BMC Genomics, 2008
Background Many studies have shown that the abundance level of gene expression is heritable. Analogous to the traditional genetic study, most researchers treat the expression of one gene as a quantitative trait and map it to expression quantitative trait
Sun Wei, Yuan Shinsheng, Li Ker-Chau
doaj   +1 more source

Using social interaction models for genetic analysis of skin damage in gilts

Genetics Selection Evolution, 2023
Background Skin damage is a trait of economic and welfare importance that results from social interactions between animals. These interactions may produce wound signs on the gilt’s skin as a result of damage behavior (i.e., fighting), biting syndromes (i.
Natália Galoro Leite, Egbert Knol, Shogo Tsuruta, Stefanie Nuphaus, Roos Vogelzang, Daniela Lourenco   +5 more
doaj   +1 more source